CDK5R2

Gene Name		cyclin-dependent kinase 5, regulatory subunit 2 (p39)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Cyclin-dependent Protein Kinase 5 Holoenzyme Complex
	Molecular Function	Lipid Binding Cyclin-dependent Protein Kinase 5 Activator Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Neuron Migration Cerebellum Development Superior Olivary Nucleus Maturation Hippocampus Development Layer Formation In Cerebral Cortex Positive Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Protein Serine/threonine Kinase Activity
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-protein Interactions		4 interactors: ACTB ACTN1 CAMK2A CDK5
Entrez ID		8941
HPRD ID		04790
Ensembl ID		ENSG00000171450
Uniprot IDs		Q13319
PDB IDs
Enriched GO Terms of Interacting Partners?		Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Adherens Junction Organization Response To Wounding Peptidyl-serine Phosphorylation Membrane Organization Regulation Of Synaptic Plasticity Cell-matrix Adhesion Organelle Organization Platelet Activation Cell Junction Assembly Cell-cell Junction Organization Response To Stress Protein Autophosphorylation Negative Regulation Of Synaptic Plasticity Cell-substrate Adhesion Cell Adhesion Protein Localization To Tight Junction Serine Phosphorylation Of STAT3 Protein Vesicle-mediated Transport Regulation Of Apoptotic Process Serine Phosphorylation Of STAT Protein Regulation Of Synaptic Transmission Negative Regulation Of Protein Export From Nucleus Regulation Of Cell Death Exocytosis Regulation Of Synaptic Vesicle Recycling Protein Localization To Cell Junction Axon Guidance Cellular Component Assembly Transport Synaptic Transmission, Dopaminergic Establishment Of Localization In Cell Behavioral Response To Cocaine Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Actin Cytoskeleton Reorganization Secretion By Cell Axonogenesis Positive Regulation Of Calcium Ion-dependent Exocytosis Actin Crosslink Formation Corpus Callosum Development Protein Localization To Synapse Axon Development Receptor Catabolic Process Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Cell Morphogenesis Involved In Neuron Differentiation Synaptic Transmission Positive Regulation Of Apoptotic Process
Tagcloud ?		aids ak1 biosynthesis cycles deepen drugable ephb2 figure hek293t hiv host kinases library ltr nfkappab overlapped p38mapk plasmid prkacb regimens repress rnai shrna silenced stably therapeutics throughput uncovers vital