CBR1

Gene Name		carbonyl reductase 1
Image
Gene Ontology Annotations	Cellular Component	Cytosol Vesicle Extracellular Vesicular Exosome
	Molecular Function	Carbonyl Reductase (NADPH) Activity Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor 15-hydroxyprostaglandin Dehydrogenase (NADP+) Activity Prostaglandin-E2 9-reductase Activity
	Biological Process	Drug Metabolic Process Arachidonic Acid Metabolic Process Cyclooxygenase Pathway Epithelial Cell Differentiation Vitamin K Metabolic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Arachidonic acid metabolism Metabolism of lipids and lipoproteins Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: EGFR ERCC8 UBC VHL
Entrez ID		873
HPRD ID		00267
Ensembl ID		ENSG00000159228
Uniprot IDs		B4DFK7 P16152
PDB IDs		1WMA 2PFG 3BHI 3BHJ 3BHM
Enriched GO Terms of Interacting Partners?		Response To Abiotic Stimulus Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of DNA Repair Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Regulation Of DNA Repair Positive Regulation Of Response To DNA Damage Stimulus Protein Ubiquitination Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Protein Modification By Small Protein Conjugation Regulation Of ERBB Signaling Pathway Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Positive Regulation Of Cellular Metabolic Process Alkanesulfonate Metabolic Process Regulation Of Response To DNA Damage Stimulus Response To UV Negative Regulation Of Apoptotic Process Positive Regulation Of DNA Metabolic Process Negative Regulation Of Programmed Cell Death G1/S Transition Of Mitotic Cell Cycle Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Cell Death ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Protein Polyubiquitination Circadian Rhythm Activation Of Phospholipase A2 Activity By Calcium-mediated Signaling Astrocyte Activation Cellular Protein Modification Process Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Positive Regulation Of Metabolic Process Response To Stress Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of MAP Kinase Activity Negative Regulation Of Mitotic Cell Cycle Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway MAPK Cascade Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Activation Of Phospholipase A2 Activity Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Proteasomal Protein Catabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition
Tagcloud ?		david degs downloaded dyrk1a egr1 encyclopedia geo gse hmgn1 hypergeometric interrogate itsn1 kegg kyoto macromolecular multiarray mycmax mzf1 nfe2 nfy olf1 ominibus pax5 rma rp58 son srebp1 tmem50b ttc3