CAT

Gene Name		catalase
Image
Gene Ontology Annotations	Cellular Component	Mitochondrial Intermembrane Space Lysosome Peroxisome Peroxisomal Membrane Peroxisomal Matrix Endoplasmic Reticulum Golgi Apparatus Cytosol Plasma Membrane Focal Adhesion Membrane Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Aminoacylase Activity Catalase Activity Receptor Binding Antioxidant Activity Oxidoreductase Activity, Acting On Peroxide As Acceptor Enzyme Binding Heme Binding Protein Homodimerization Activity Metal Ion Binding NADP Binding
	Biological Process	Response To Reactive Oxygen Species Osteoblast Differentiation Ureteric Bud Development Response To Hypoxia Purine Nucleobase Metabolic Process Purine Nucleotide Catabolic Process Triglyceride Metabolic Process Aging Cholesterol Metabolic Process Aerobic Respiration UV Protection Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Hemoglobin Metabolic Process Negative Regulation Of NF-kappaB Transcription Factor Activity Response To Vitamin E Hydrogen Peroxide Catabolic Process Negative Regulation Of Apoptotic Process Small Molecule Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Tetramerization Protein Homotetramerization Positive Regulation Of Cell Division Nucleobase-containing Small Molecule Metabolic Process Response To Hyperoxia Cellular Response To Growth Factor Stimulus
Pathways		Purine catabolism Purine metabolism Detoxification of Reactive Oxygen Species Metabolism of nucleotides
Drugs		Fomepizole Heme
Diseases
GWAS
Protein-protein Interactions		8 interactors: ABL1 ABL2 APP EHHADH KEAP1 PTPN11 SUMO4 TLR10
Entrez ID		847
HPRD ID		00282
Ensembl ID		ENSG00000121691
Uniprot IDs		P04040
PDB IDs		1DGB 1DGF 1DGG 1DGH 1F4J 1QQW
Enriched GO Terms of Interacting Partners?		Platelet-derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Interferon-gamma Secretion Collateral Sprouting Neuromuscular Process Controlling Balance Bergmann Glial Cell Differentiation Innate Immune Response Neuron Remodeling Positive Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Positive Regulation Of Interleukin-2 Secretion Axon Guidance Regulation Of Protein Secretion Positive Regulation Of Non-canonical Wnt Signaling Pathway Cellular Protein Modification Process Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of ERK1 And ERK2 Cascade Neuromuscular Process Regulation Of Cytokine Secretion Regulation Of Wnt Signaling Pathway, Planar Cell Polarity Pathway Axonogenesis Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Axon Development Immune Response Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Defense Response Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Endothelial Cell Apoptotic Process Regulation Of Protein Transport Regulation Of Secretion Neuron Projection Morphogenesis Negative Regulation Of Cell Adhesion Regulation Of Establishment Of Protein Localization Neuron Maturation Cellular Protein Metabolic Process Cell Morphogenesis Involved In Differentiation Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Interleukin-2 Production Brain Development Peptidyl-tyrosine Autophosphorylation Regulation Of Actin Cytoskeleton Reorganization Regulation Of Extracellular Matrix Organization Positive Regulation Of Oxidoreductase Activity Regulation Of Protein Localization Head Development Astrocyte Differentiation Neuron Projection Development Positive Regulation Of Cell Cycle Cell Projection Morphogenesis Cellular Calcium Ion Homeostasis
Tagcloud ?		alternatives chloramphenicol competition constructs designated electrophoretic element emsa exactly flanking gggaaggcggagtcc ggrgyyn ifn inducibility inducible isre kcs mutagenesis mutational nnrrrgg pkr possessing purine pyrimidine replaced stands tata transfection whereby