HORMAD1

Gene Name		HORMA domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Condensed Nuclear Chromosome Nucleus Chromosome
	Molecular Function
	Biological Process	Blastocyst Development Meiotic Nuclear Division Synaptonemal Complex Assembly Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis Meiotic Sister Chromatid Cohesion Meiotic Recombination Checkpoint Regulation Of Homologous Chromosome Segregation
Pathways
Drugs
Diseases
GWAS		Rhegmatogenous retinal detachment ( 23585552)
Protein-protein Interactions		2 interactors: BRCA1 MSL1
Entrez ID		84072
HPRD ID		11396
Ensembl ID		ENSG00000143452
Uniprot IDs		Q86X24
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Histone H3-K9 Acetylation Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Cellular Response To Indole-3-methanol Negative Regulation Of Centriole Replication Dosage Compensation By Inactivation Of X Chromosome Protein K6-linked Ubiquitination Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation Regulation Of Centriole Replication Histone H4-K16 Acetylation Positive Regulation Of Histone H3-K4 Methylation Regulation Of Histone H4 Acetylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Negative Regulation Of Fatty Acid Biosynthetic Process DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of Histone Methylation Negative Regulation Of Centrosome Duplication Regulation Of DNA Methylation Negative Regulation Of Histone Acetylation Positive Regulation Of Histone Acetylation Negative Regulation Of Peptidyl-lysine Acetylation Regulation Of Histone H3-K4 Methylation Negative Regulation Of Protein Acetylation Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Postreplication Repair Regulation Of Transcription From RNA Polymerase III Promoter Negative Regulation Of Fatty Acid Metabolic Process Regulation Of Gene Expression By Genetic Imprinting Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Genetic Imprinting Regulation Of Fatty Acid Biosynthetic Process Positive Regulation Vascular Endothelial Growth Factor Production G2 DNA Damage Checkpoint Positive Regulation Of Histone Methylation Positive Regulation Of DNA Repair Androgen Receptor Signaling Pathway Regulation Of Centrosome Duplication Protein Autoubiquitination Regulation Of Histone Acetylation Negative Regulation Of Lipid Biosynthetic Process Negative Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Centrosome Cycle Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
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