ALDH5A1

Gene Name		aldehyde dehydrogenase 5 family, member A1
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Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix
	Molecular Function	Aldehyde Dehydrogenase (NAD) Activity Succinate-semialdehyde Dehydrogenase (NAD+) Activity Succinate-semialdehyde Dehydrogenase [NAD(P)+] Activity Protein Homodimerization Activity
	Biological Process	Glucose Metabolic Process Acetate Metabolic Process Succinate Metabolic Process Glutamate Metabolic Process Glutamine Metabolic Process Glycerophospholipid Metabolic Process Glucosylceramide Metabolic Process Galactosylceramide Metabolic Process Glutathione Metabolic Process Synaptic Transmission Neurotransmitter Secretion Central Nervous System Development Gamma-aminobutyric Acid Catabolic Process Post-embryonic Development Respiratory Electron Transport Chain Neurotransmitter Catabolic Process Short-chain Fatty Acid Metabolic Process Protein Homotetramerization
Pathways		Neurotransmitter Release Cycle Degradation of GABA GABA synthesis, release, reuptake and degradation Transmission across Chemical Synapses
Drugs		Succinic acid NADH Valproic Acid Chlormerodrin
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 22001757)
Protein-protein Interactions		2 interactors: ABAT MAGEA11
Entrez ID		7915
HPRD ID		08361
Ensembl ID		ENSG00000112294
Uniprot IDs		P51649 Q546H9
PDB IDs		2W8N 2W8O 2W8P 2W8Q 2W8R
Enriched GO Terms of Interacting Partners?		Gamma-aminobutyric Acid Catabolic Process Gamma-aminobutyric Acid Metabolic Process Behavioral Response To Cocaine Neurotransmitter Catabolic Process Copulation Neurotransmitter Metabolic Process Response To Iron Ion Response To Nicotine Negative Regulation Of Blood Pressure Response To Cocaine Mating Response To Ammonium Ion Neurotransmitter Secretion Cellular Amino Acid Catabolic Process Regulation Of Neurotransmitter Levels Response To Ethanol Response To Alkaloid Adult Behavior Neurotransmitter Transport Regulation Of Blood Pressure Carboxylic Acid Catabolic Process Locomotory Behavior Response To Hypoxia Blood Circulation Response To Metal Ion Single-organism Behavior Cellular Amino Acid Metabolic Process Response To Inorganic Substance Secretion By Cell Response To Drug Monocarboxylic Acid Metabolic Process Synaptic Transmission Behavior Secretion
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