PRRG4

Gene Name		proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Integral Component Of Membrane
	Molecular Function	Molecular_function Calcium Ion Binding
	Biological Process	Biological_process
Pathways
Drugs
Diseases
GWAS		Parkinson's disease (age of onset) ( 19772629)
Protein-protein Interactions		7 interactors: AOC3 BCL10 HDAC1 HLA-C RBBP8 UBE2K VEGFA
Entrez ID		79056
HPRD ID		15187
Ensembl ID		ENSG00000135378
Uniprot IDs		Q9BZD6
PDB IDs
Enriched GO Terms of Interacting Partners?		Response To Stress Embryo Development Positive Regulation Of Protein Kinase D Signaling Basophil Chemotaxis Positive Regulation Of Mast Cell Cytokine Production Positive Regulation Of Protein Localization To Early Endosome Positive Regulation Of Retinal Ganglion Cell Axon Guidance Coronary Vein Morphogenesis Primitive Erythrocyte Differentiation VEGF-activated Neuropilin Signaling Pathway Lymphotoxin A Biosynthetic Process Interleukin-6 Biosynthetic Process Response To Stimulus Regulation Of Proteolysis Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing Positive Regulation Of Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Positive Regulation Of Histone Deacetylase Activity Tube Formation Negative Regulation Of Transcription From RNA Polymerase II Promoter Chordate Embryonic Development Positive Regulation Of Lymphangiogenesis Cardiac Vascular Smooth Muscle Cell Development Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Positive Regulation Of Mast Cell Chemotaxis Negative Regulation Of Mature B Cell Apoptotic Process Regulation Of Retinal Ganglion Cell Axon Guidance Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway Embryo Development Ending In Birth Or Egg Hatching Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway Regulation Of Histone Deacetylase Activity Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Immune System Process Interleukin-6 Production Positive Regulation Of Deacetylase Activity Coronary Artery Morphogenesis Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Cell Migration Involved In Sprouting Angiogenesis Cardiac Vascular Smooth Muscle Cell Differentiation Apoptotic Process Negative Regulation Of Cell Death Positive Regulation Of Interleukin-8 Biosynthetic Process Positive Regulation Of Axon Extension Involved In Axon Guidance Cardiac Muscle Fiber Development Programmed Cell Death
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