VCL

Gene Name		vinculin
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Gene Ontology Annotations	Cellular Component	Extracellular Region Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Adherens Junction Cell-cell Adherens Junction Fascia Adherens Focal Adhesion Actin Cytoskeleton Cell-substrate Junction Vesicle Costamere Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Dystroglycan Binding Actin Binding Structural Molecule Activity Protein Binding Beta-catenin Binding Alpha-catenin Binding Cadherin Binding
	Biological Process	Morphogenesis Of An Epithelium Platelet Degranulation Movement Of Cell Or Subcellular Component Muscle Contraction Cell Adhesion Cell-matrix Adhesion Blood Coagulation Lamellipodium Assembly Platelet Activation Negative Regulation Of Cell Migration Adherens Junction Assembly Protein Localization To Cell Surface Apical Junction Assembly Axon Extension Platelet Aggregation Epithelial Cell-cell Adhesion
Pathways		Response to elevated platelet cytosolic Ca2+ Smooth Muscle Contraction Platelet degranulation Platelet activation, signaling and aggregation
Drugs
Diseases
GWAS		Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328)
Protein-protein Interactions		27 interactors: ABI2 ACTA1 ACTN1 C19orf57 CDH1 CLTC CORO2B CTNNA1 GSN NRAP PKD1 PRKCA PRPF40A PSME1 PTK2 PXN RAVER1 SELE SORBS1 SORBS2 SRC TEKT1 TGFB1I1 TLN1 TRIP6 TUBA1A VASP
Entrez ID		7414
HPRD ID		01900
Ensembl ID		ENSG00000035403
Uniprot IDs		B3KXA2 P18206
PDB IDs		1RKC 1RKE 1SYQ 1TR2 1YDI 2GWW 2HSQ 2IBF 3H2U 3H2V 3MYI 3RF3 3S90 3TJ5 3TJ6 3VF0 4DJ9 4EHP
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Cell Junction Assembly Cell-cell Junction Organization Actin Filament-based Process Organelle Organization Adherens Junction Organization Actin Filament Organization Actin Cytoskeleton Organization Cell Adhesion Cellular Component Assembly Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell-substrate Junction Assembly Regulation Of Cellular Component Organization Regulation Of Cellular Component Movement Focal Adhesion Assembly Signal Complex Assembly Cell-cell Junction Assembly Cell-substrate Adhesion Movement Of Cell Or Subcellular Component Adherens Junction Assembly Regulation Of Cell Motility Positive Regulation Of Signal Transduction Regulation Of Locomotion Response To Organic Substance Response To Wounding Cell-matrix Adhesion Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Cell Projection Organization Cell Differentiation Positive Regulation Of Transferase Activity Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Anatomical Structure Morphogenesis Regulation Of Body Fluid Levels Platelet Activation Regulation Of Cell Migration Wound Healing Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Locomotion Blood Coagulation Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Hemostasis Cellular Response To Stimulus Protein Complex Assembly Cell Development Cellular Response To Organonitrogen Compound Integrin-mediated Signaling Pathway Cellular Response To Organic Substance
Tagcloud ?		34a 34c analyse chimeras crick destabilizing differs fkbp8 implement micrornas mir mirna nucleotides observe overlap overlapping pairing perfect preferential psilac raising repress repressed resource seed subsets untranslated want watson