SIPA1

Gene Name		signal-induced proliferation-associated 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Golgi Apparatus Cytosol Plasma Membrane Transport Vesicle Protein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	GTPase Activator Activity Protein Binding Protein C-terminus Binding Rap GTPase Activator Activity
	Biological Process	Cytoskeleton Organization Negative Regulation Of Cell Adhesion Signal Transduction Cell Proliferation Negative Regulation Of Cell Growth Positive Regulation Of Rap GTPase Activity Intracellular Signal Transduction Cellular Response To Water Deprivation Positive Regulation Of GTPase Activity Negative Regulation Of Cell Cycle
Pathways		Rap1 signalling Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: CDKN1A DVL1 RFWD2
Entrez ID		6494
HPRD ID		03713
Ensembl ID		ENSG00000213445
Uniprot IDs		F6RY50 Q96FS4
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Regulation Of Cell Cycle Arrest Mitotic DNA Integrity Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Signal Transduction By P53 Class Mediator Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Response To Ionizing Radiation Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cellular Protein Catabolic Process DNA Damage Checkpoint Mitotic Cell Cycle Checkpoint Positive Regulation Of Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Protein Kinase Activity Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Positive Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Negative Regulation Of Kinase Activity Convergent Extension Involved In Neural Plate Elongation Positive Regulation Of Cell Cycle Positive Regulation Of Proteolysis Negative Regulation Of Transferase Activity Intracellular Signal Transduction Negative Regulation Of Protein Phosphorylation Collateral Sprouting Intestinal Epithelial Cell Maturation Regulation Of Cellular Protein Metabolic Process Convergent Extension Involved In Organogenesis Regulation Of Protein Catabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Phosphorylation
Tagcloud ?		1307t allele arms chi confer conferred ecm extra genotype genotyping hyderabad insilco institute know modifier modulates nizam online polymorphism processing1 reconfirmed rrp1b rrp1b1307 rrp1b1307tt rs9306160 rural sciences tt urban