ELMO2

Gene Name		engulfment and cell motility 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Membrane
	Molecular Function	Protein Binding SH3 Domain Binding Receptor Tyrosine Kinase Binding
	Biological Process	Apoptotic Process Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell Chemotaxis
Pathways		Signaling by VEGF Fcgamma receptor (FCGR) dependent phagocytosis VEGFA-VEGFR2 Pathway Regulation of actin dynamics for phagocytic cup formation Innate Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: DOCK1 RHOG
Entrez ID		63916
HPRD ID		12103
Ensembl ID		ENSG00000062598
Uniprot IDs		B4DRL5 B4DZ20 F5GZP8 Q7Z5G9 Q96JJ3
PDB IDs
Enriched GO Terms of Interacting Partners?		Axon Guidance Blood Coagulation Hemostasis Axonogenesis Axon Development Regulation Of Body Fluid Levels Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Chemotaxis Small GTPase Mediated Signal Transduction Neuron Projection Morphogenesis Response To Wounding Cell Morphogenesis Involved In Differentiation Positive Regulation Of GTPase Activity Activation Of Rac GTPase Activity Phagocytosis, Engulfment Regulation Of GTPase Activity Neuron Projection Development Cell Migration Cell Projection Morphogenesis Cell Part Morphogenesis Cell Motility Regulation Of Ruffle Assembly Membrane Invagination Rac Protein Signal Transduction Neuron Development Positive Regulation Of Hydrolase Activity Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Cell Morphogenesis Positive Regulation Of Protein Localization To Plasma Membrane Neuron Differentiation Cell Projection Organization Locomotion Activation Of Rho GTPase Activity Regulation Of Establishment Of Protein Localization To Plasma Membrane Movement Of Cell Or Subcellular Component Positive Regulation Of Catalytic Activity Regulation Of Protein Localization To Plasma Membrane Generation Of Neurons Activation Of Ras GTPase Activity Positive Regulation Of Rac GTPase Activity Rho Protein Signal Transduction Neurogenesis Cell Development Response To External Stimulus Intracellular Signal Transduction Vascular Endothelial Growth Factor Receptor Signaling Pathway Nervous System Development Regulation Of Cell Projection Assembly Regulation Of Catalytic Activity
Tagcloud ?		adhesion adhesions cadherin canine completion contacts coordinate coordination darby dock dock1 dynamic exchange gtpase guanine integrin interference localize madin rac recruits reorganization requiring rho screen spreading subsequently unexpected