PTPN3

Gene Name		protein tyrosine phosphatase, non-receptor type 3
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cytoskeleton Cytoplasmic Side Of Plasma Membrane
	Molecular Function	Phosphotyrosine Binding Protein Tyrosine Phosphatase Activity Protein Binding Cytoskeletal Protein Binding Sodium Channel Regulator Activity ATPase Binding
	Biological Process	Protein Dephosphorylation Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Membrane Protein Ectodomain Proteolysis Liver Regeneration Regulation Of Membrane Depolarization During Action Potential Regulation Of Sodium Ion Transmembrane Transporter Activity
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		14 interactors: ADAM17 AKR1C1 CD247 DIP2A GHR LMO1 NXT2 VCP WDR6 YWHAB YWHAG YWHAQ ZAP70 ZCCHC10
Entrez ID		5774
HPRD ID		06767
Ensembl ID		ENSG00000070159
Uniprot IDs		B7Z3V3 B7Z9V1 B7ZA03 P26045 Q8N4S3
PDB IDs		2B49
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Cellular Response To Hormone Stimulus Regulation Of Mitochondrion Organization Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Positive Regulation Of Signal Transduction Apoptotic Signaling Pathway Regulation Of Apoptotic Process JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Response To Peptide Hormone Growth Hormone Receptor Signaling Pathway Regulation Of Cell Death Cellular Response To Organonitrogen Compound Cellular Response To Growth Hormone Stimulus Response To Hormone Response To Peptide Apoptotic Process Programmed Cell Death Intrinsic Apoptotic Signaling Pathway Cell Death Positive Regulation Of Apoptotic Signaling Pathway Death Response To Growth Hormone Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Intracellular Signal Transduction Cellular Response To Organic Substance Positive Regulation Of Cell Death Positive Regulation Of Intracellular Transport Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway JAK-STAT Cascade Regulation Of Protein Kinase Activity Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination Protein Transport Signaling T Cell Differentiation In Thymus Regulation Of Kinase Activity Cell Communication Establishment Of Protein Localization Response To Organonitrogen Compound Immune Response-regulating Cell Surface Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Multicellular Organismal Metabolic Process Beta Selection Positive Regulation Of Protein Modification Process
Tagcloud ?		adaptor advance border cascades dephosphorylation doi dptpmeg drosophila egfr endocytosis eps15 ferm homolog impairs lysosomal morphogenesis onc oncogene online pdz publication raft scaffolding september suppress trafficking tumorigenicity wing xenograft