KLK6

Gene Name		kallikrein-related peptidase 6
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleoplasm Nucleolus Cytoplasm Mitochondrion Endoplasmic Reticulum Microtubule Cytoskeleton Nuclear Membrane Intercellular Bridge
	Molecular Function	Serine-type Endopeptidase Activity Protein Binding
	Biological Process	Proteolysis Central Nervous System Development Response To Wounding Regulation Of Neuron Projection Development Protein Processing Protein Autoprocessing Collagen Catabolic Process Tissue Regeneration Hormone Metabolic Process Myelination Amyloid Precursor Protein Metabolic Process Regulation Of Cell Differentiation Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Neuron Death
Pathways
Drugs		Benzamidine
Diseases
GWAS
Protein-protein Interactions		3 interactors: SERPINC1 SERPINF2 SNCA
Entrez ID		5653
HPRD ID		04037
Ensembl ID		ENSG00000167755
Uniprot IDs		Q92876
PDB IDs		1GVL 1L2E 1LO6 3VFE 4D8N
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Endopeptidase Activity Negative Regulation Of Peptidase Activity Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Regulation Of Proteolysis Negative Regulation Of Catalytic Activity Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Blood Coagulation Negative Regulation Of Protein Metabolic Process Regulation Of Wound Healing Negative Regulation Of Thrombin Receptor Signaling Pathway Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Norepinephrine Uptake Regulation Of Blood Coagulation, Intrinsic Pathway Positive Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Glutathione Peroxidase Activity Negative Regulation Of Mitochondrial Electron Transport, NADH To Ubiquinone Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Serotonin Uptake Negative Regulation Of Dopamine Metabolic Process Negative Regulation Of Cellular Respiration Negative Regulation Of Oxidative Phosphorylation Negative Regulation Of Synaptic Transmission, Dopaminergic Regulation Of Blood Vessel Size By Renin-angiotensin Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Response To Iron(II) Ion Cellular Response To Copper Ion Extracellular Matrix Organization Negative Regulation Of Cellular Metabolic Process Extracellular Structure Organization Regulation Of Protein Metabolic Process Regulation Of Synaptic Vesicle Recycling Negative Regulation Of Plasminogen Activation Blood Coagulation Hemostasis Regulation Of Catalytic Activity Regulation Of Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Fibrinolysis Regulation Of Oxidative Phosphorylation Positive Regulation Of Inositol Phosphate Biosynthetic Process Regulation Of Hydrogen Peroxide Metabolic Process Dopamine Transport Regulation Of Cytoskeleton Organization Regulation Of Glutamate Secretion Dopamine Biosynthetic Process
Tagcloud ?		abundance abundant acrylic capture captured depletion eluate elution facilitated fractionation hydrogel ibp2 igf1 incubated interfere irreversibly isk5 isopropylacrylamide opens orders particles perspectives platforms plf4 proteome protocols srm supernatants trapped