EAF2

Gene Name		ELL associated factor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Elongation Factor Complex Nuclear Speck ELL-EAF Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription Protein Binding
	Biological Process	Transcription, DNA-templated Apoptotic Process Negative Regulation Of Cell Growth Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		7 interactors: BEND7 BIRC2 ELL TCEA1 TCEA2 TFPT TRIM23
Entrez ID		55840
HPRD ID		09634
Ensembl ID		ENSG00000145088
Uniprot IDs		B4DWJ3 Q96CJ1
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription, Elongation DNA-templated Transcription, Elongation Transcription, DNA-templated Positive Regulation Of Viral Transcription RNA Biosynthetic Process Transcription Elongation From RNA Polymerase II Promoter Regulation Of Viral Transcription Positive Regulation Of Viral Process Viral Process RNA Metabolic Process Positive Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Protein Monoubiquitination Positive Regulation Of Protein K48-linked Ubiquitination Positive Regulation Of Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Ripoptosome Assembly Involved In Necroptotic Process Regulation Of Viral Process Translational Elongation Regulation Of Protein Monoubiquitination Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process SnRNA Transcription From RNA Polymerase III Promoter Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein K63-linked Ubiquitination Positive Regulation Of Transcription From RNA Polymerase II Promoter SnRNA Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Nitrogen Compound Metabolic Process SnRNA Transcription Positive Regulation Of Transcription From RNA Polymerase III Promoter Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Negative Regulation Of Necroptotic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Negative Regulation Of Necrotic Cell Death Regulation Of RIG-I Signaling Pathway Regulation Of Necroptotic Process Negative Regulation Of Hydrolase Activity Positive Regulation Of Macromolecule Biosynthetic Process
Tagcloud ?		aberrant aim2 bh3 bik complements constitutive cooperates diffuse dlbcl expansion forkhead foxp1 harakiri lymphoid lymphoma lymphomagenesis lymphomas mucosa next oncogene proapoptotic promote rassf6 regarded relying represses repression tp53inp1 tp63