WDR12

Gene Name		WD repeat domain 12
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Nucleolus Preribosome, Large Subunit Precursor PeBoW Complex
	Molecular Function	Protein Binding Ribonucleoprotein Complex Binding
	Biological Process	Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Maturation Of 5.8S RRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Notch Signaling Pathway Cell Proliferation Ribosomal Large Subunit Biogenesis
Pathways
Drugs
Diseases
GWAS		Coronary heart disease ( 21378990) Myocardial infarction (early onset) ( 19198609)
Protein-protein Interactions		2 interactors: HIST1H1C NOTCH1
Entrez ID		55759
HPRD ID		18295
Ensembl ID
Uniprot IDs		Q53T99 Q9GZL7
PDB IDs
Enriched GO Terms of Interacting Partners?		Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Venous Endothelial Cell Differentiation Cardiac Right Atrium Morphogenesis Mitral Valve Formation Vasculogenesis Involved In Coronary Vascular Morphogenesis Negative Regulation Of Pro-B Cell Differentiation Growth Involved In Heart Morphogenesis Atrioventricular Node Development Coronary Vein Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cell Migration Involved In Endocardial Cushion Formation Cardiac Right Ventricle Formation Negative Regulation Of Endothelial Cell Chemotaxis Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Negative Regulation Of Photoreceptor Cell Differentiation Regulation Of Pro-B Cell Differentiation Aortic Valve Morphogenesis Cardiac Vascular Smooth Muscle Cell Development Compartment Pattern Specification Regulation Of Extracellular Matrix Assembly Positive Regulation Of Transcription Of Notch Receptor Target Mitral Valve Morphogenesis Apoptotic Process Involved In Embryonic Digit Morphogenesis Pericardium Morphogenesis Glomerular Mesangial Cell Development Nucleosome Positioning Mitral Valve Development Coronary Artery Morphogenesis Mesangial Cell Development Cardiac Vascular Smooth Muscle Cell Differentiation Regulation Of Somitogenesis Renal Interstitial Fibroblast Development Interleukin-4 Secretion Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Notch Signaling Involved In Heart Development Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Auditory Receptor Cell Fate Commitment Pulmonary Valve Morphogenesis Arterial Endothelial Cell Differentiation Positive Regulation Of Astrocyte Differentiation Endocardial Cell Differentiation Regulation Of Transcription From RNA Polymerase II Promoter Involved In Myocardial Precursor Cell Differentiation Endocardium Morphogenesis Vascular Smooth Muscle Cell Development Blood Vessel Endothelial Cell Differentiation Negative Regulation Of Glial Cell Proliferation Venous Blood Vessel Morphogenesis Interleukin-4 Production Coronary Vasculature Morphogenesis Regulation Of Secondary Heart Field Cardioblast Proliferation
Tagcloud ?		applying cholesterol cxcl12 effectors exact fam174a gfp gwas infarction internalization inversely ldl limitations loci modifies pafah1b1 powerful rarely rnai scalable sez6l surprisingly systematic tagged tbl2 trait traits unbiased unravel