MFN1

Gene Name		mitofusin 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Outer Membrane Integral Component Of Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding
	Biological Process	Mitochondrial Fusion
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: BAK1 PARK2
Entrez ID		55669
HPRD ID		16344
Ensembl ID		ENSG00000171109
Uniprot IDs		Q8IWA4
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mitochondrion Organization Regulation Of Mitochondrion Organization Response To Endoplasmic Reticulum Stress Response To Toxic Substance Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Regulation Of Binding Positive Regulation Of Protein Linear Polyubiquitination Fibroblast Apoptotic Process Positive Regulation Of Proteolysis Negative Regulation Of Protein Phosphorylation Dopamine Uptake Involved In Synaptic Transmission Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Dopamine B Cell Negative Selection Mitochondrion Organization Negative Regulation Of Phosphorylation Positive Regulation Of Organelle Organization Response To Mycotoxin Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Post-embryonic Camera-type Eye Morphogenesis Response To Oxidative Stress Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Manganese Ion Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Protein K27-linked Ubiquitination Protein K29-linked Ubiquitination Negative Regulation Of Mitochondrial Fusion Metal Ion Homeostasis Response To Inorganic Substance Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrial Fusion Negative Regulation Of Glucokinase Activity Neuron Cellular Homeostasis Ion Homeostasis Positive Regulation Of Oxidative Stress-induced Cell Death Protein K6-linked Ubiquitination Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Negative Regulation Of Oxidative Stress-induced Neuron Death Apoptotic Process Involved In Patterning Of Blood Vessels Thymocyte Apoptotic Process B Cell Apoptotic Process Post-embryonic Organ Morphogenesis Positive Regulation Of Cell Death Regulation Of Ion Transport Positive Regulation Of Mitochondrial Fission Regulation Of Proteolysis
Tagcloud ?		app atrophy biogenesis cognitive compensate defect deficits drp1 dynamin feature fis1 fission injected mfn2 mitochondria mitochondrial mitofusion nsc nscs opa1 optic prominent ps1 rescue susceptible tg transplantation veh vehicle