PRG2

Gene Name		proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Transport Vesicle Extracellular Vesicular Exosome
	Molecular Function	Heparin Binding Carbohydrate Binding
	Biological Process	Defense Response To Nematode Immune Response Negative Regulation Of Interleukin-10 Production Positive Regulation Of Interleukin-4 Production Defense Response To Bacterium
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 22412388)
Protein-protein Interactions		7 interactors: AGT AKT1 CHD3 CSF2 PAPPA PRKCZ RBM48
Entrez ID		5553
HPRD ID		09283
Ensembl ID
Uniprot IDs		A6XMW0 P13727
PDB IDs		1H8U 2BRS
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Cellular Ketone Metabolic Process Cell Activation Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Phosphorylation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Peptidyl-tyrosine Phosphorylation Female Pregnancy Positive Regulation Of Cell Proliferation Positive Regulation Of Cell Differentiation Positive Regulation Of Macrophage Derived Foam Cell Differentiation Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Glucose Import Positive Regulation Of Oxidoreductase Activity Negative Regulation Of Cell Death Positive Regulation Of Glucose Transport Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Macrophage Derived Foam Cell Differentiation Regulation Of Protein Phosphorylation Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Signal Transduction Positive Regulation Of Cytokine Production Positive Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Transmembrane Transport Regulation Of Glucose Import Positive Regulation Of Endothelial Cell Migration Regulation Of Vasoconstriction Negative Regulation Of Signaling Negative Regulation Of Hydrolase Activity Regulation Of Nitric Oxide Biosynthetic Process Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Lipid Biosynthetic Process Positive Regulation Of Protein Metabolic Process Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Sodium Ion Transport Positive Regulation Of Signal Transduction Positive Regulation Of Phospholipase Activity Regulation Of Phosphorylation Reproductive Process Cellular Response To Mechanical Stimulus Positive Regulation Of Protein Kinase Activity Regulation Of Phospholipase Activity Regulation Of Oxidoreductase Activity Developmental Cell Growth Positive Regulation Of Peptidyl-serine Phosphorylation
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