STRADB

Gene Name		STE20-related kinase adaptor beta
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Mitotic Cell Cycle Cell Morphogenesis Protein Phosphorylation Protein Export From Nucleus Cell Cycle Arrest JNK Cascade Insulin Receptor Signaling Pathway Activation Of Protein Kinase Activity Intracellular Signal Transduction Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Insulin receptor signalling cascade IRS-mediated signalling Regulation of AMPK activity via LKB1 mTOR signalling IRS-related events mTOR signalling IGF1R signaling cascade IRS-related events triggered by IGF1R IRS-mediated signalling Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Energy dependent regulation of mTOR by LKB1-AMPK PKB-mediated events PI3K Cascade PKB-mediated events PI3K Cascade Signaling by Insulin receptor
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: CAB39 GRB2 MAP3K7 STK11 TRAF6 XIAP
Entrez ID		55437
HPRD ID		09546
Ensembl ID		ENSG00000082146
Uniprot IDs		Q9C0K7
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Stress Activation Of Protein Kinase Activity Intracellular Signal Transduction Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Immune Response Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Protein Modification Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process T Cell Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Protein Kinase Activity Positive Regulation Of Protein Metabolic Process Positive Regulation Of Signal Transduction Positive Regulation Of Kinase Activity Regulation Of Immune System Process Regulation Of Phosphorylation Protein Heterooligomerization Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Transferase Activity Insulin Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Cell Surface Receptor Signaling Pathway Positive Regulation Of Immune Response Positive Regulation Of T Cell Cytokine Production Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Metabolic Process Response To Stress Positive Regulation Of Protein Phosphorylation Regulation Of Intracellular Signal Transduction Positive Regulation Of T Cell Activation Regulation Of Protein Kinase Activity Cellular Response To Insulin Stimulus Positive Regulation Of Homotypic Cell-cell Adhesion Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Regulation Of T Cell Cytokine Production Fc-epsilon Receptor Signaling Pathway Regulation Of Kinase Activity Cellular Response To Organic Substance Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Activation Of NF-kappaB-inducing Kinase Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Phosphorylation Fc Receptor Signaling Pathway Positive Regulation Of Immune System Process Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Protein Serine/threonine Kinase Activity Positive Regulation Of Interleukin-2 Production
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