ELP3

Gene Name		elongator acetyltransferase complex subunit 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Acetyltransferase Complex Nucleolus Cytoplasm Transcription Elongation Factor Complex Elongator Holoenzyme Complex
	Molecular Function	RNA Polymerase II Core Binding Protein Binding Phosphorylase Kinase Regulator Activity H3 Histone Acetyltransferase Activity H4 Histone Acetyltransferase Activity Metal Ion Binding Iron-sulfur Cluster Binding
	Biological Process	Neuron Migration TRNA Wobble Uridine Modification Chromatin Organization Regulation Of Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Central Nervous System Development Positive Regulation Of Cell Migration Histone H3 Acetylation Histone H4 Acetylation Regulation Of Protein Kinase Activity
Pathways		Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-protein Interactions		6 interactors: CTDP1 HIST1H4A HIST2H3C IKBKAP SMAD1 SMURF1
Entrez ID		55140
HPRD ID		10936
Ensembl ID		ENSG00000134014
Uniprot IDs		Q9H9T3
PDB IDs
Enriched GO Terms of Interacting Partners?		Gene Silencing DNA Methylation On Cytosine Chromatin Silencing At RDNA Regulation Of Gene Expression, Epigenetic Chromatin Silencing Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process DNA Methylation Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Gene Expression, Epigenetic BMP Signaling Pathway DNA-templated Transcription, Elongation DNA Modification Cellular Protein Modification Process Gene Expression Transforming Growth Factor Beta Receptor Signaling Pathway Histone H4-K20 Demethylation Cellular Response To Transforming Growth Factor Beta Stimulus Transcription From RNA Polymerase II Promoter Response To Transforming Growth Factor Beta Regulation Of Ossification Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Nucleic Acid-templated Transcription Cellular Protein Metabolic Process Negative Regulation Of Megakaryocyte Differentiation Nucleobase-containing Compound Metabolic Process Primary MiRNA Processing Protein Complex Assembly Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Osteoblast Fate Commitment Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Hematopoietic Progenitor Cell Differentiation DNA Replication-dependent Nucleosome Assembly Exit From Mitosis SMAD Protein Complex Assembly Negative Regulation Of Gene Expression Nitrogen Compound Metabolic Process Protein Metabolic Process Mesodermal Cell Fate Commitment Methylation Regulation Of Megakaryocyte Differentiation Protein Localization To Cell Surface Receptor Catabolic Process Cardiac Muscle Cell Proliferation
Tagcloud ?		aberrant alternative arrdc3 carcinomas cpg detect ductal explore follows frequency gata5 grades hypermethylation idcs inactivate inactivation islands lower lymph matched methylated methylation mnts node pax6 promoter represents suppressor unmethylated