PLTP

Gene Name		phospholipid transfer protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Lipid Binding
	Biological Process	Lipid Metabolic Process Lipid Transport Vitamin E Biosynthetic Process Sperm Motility
Pathways
Drugs
Diseases
GWAS		HDL cholesterol ( 19060906 20686565) Inflammatory bowel disease ( 23128233) Lipid metabolism phenotypes ( 22286219 19936222) Metabolite levels ( 22916037) Triglycerides ( 19060906 20686565)
Protein-protein Interactions		4 interactors: ABCA1 APOA1 APOA2 APOE
Entrez ID		5360
HPRD ID		01399
Ensembl ID		ENSG00000100979
Uniprot IDs		B3KUE5 B4DDD5 P55058
PDB IDs
Enriched GO Terms of Interacting Partners?		High-density Lipoprotein Particle Assembly Phospholipid Efflux Reverse Cholesterol Transport Protein-lipid Complex Assembly Cholesterol Efflux Regulation Of Cholesterol Transport High-density Lipoprotein Particle Clearance Regulation Of Plasma Lipoprotein Particle Levels Cholesterol Transport Sterol Transport Positive Regulation Of Cholesterol Esterification Cholesterol Homeostasis Sterol Homeostasis Regulation Of Cholesterol Esterification Regulation Of Lipid Transport Phospholipid Transport Cholesterol Metabolic Process Lipid Homeostasis Sterol Metabolic Process High-density Lipoprotein Particle Remodeling Lipoprotein Metabolic Process Plasma Lipoprotein Particle Remodeling Positive Regulation Of Steroid Metabolic Process Regulation Of Cdc42 Protein Signal Transduction Plasma Lipoprotein Particle Clearance Steroid Metabolic Process Lipid Transport Anion Homeostasis Lipid Localization Alcohol Metabolic Process Negative Regulation Of Very-low-density Lipoprotein Particle Remodeling Organic Anion Transport Phototransduction, Visible Light Retinoid Metabolic Process Diterpenoid Metabolic Process Detection Of Visible Light Phototransduction Regulation Of Steroid Metabolic Process Detection Of Light Stimulus Regulation Of Intestinal Cholesterol Absorption Protein Oxidation Lipoprotein Biosynthetic Process Negative Regulation Of Cytokine Secretion Involved In Immune Response Isoprenoid Metabolic Process Anion Transport Phospholipid Homeostasis Peptidyl-methionine Modification Peripheral Nervous System Axon Regeneration Triglyceride-rich Lipoprotein Particle Remodeling Low-density Lipoprotein Particle Remodeling
Tagcloud ?		abca1 abcg5 abcg8 atorvastatin causal challenging chow excised fads1 gwas hfd hypertensive list loci lpl madd nominally nr1h3 orthologs overlapped pcsk9 qpcr qtl responded spontaneously stac3 staged suggestive timd4