PKHD1

Gene Name		polycystic kidney and hepatic disease 1 (autosomal recessive)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Centrosome Integral Component Of Membrane Apical Plasma Membrane Anchored Component Of External Side Of Plasma Membrane Ciliary Basal Body Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome Primary Cilium Mitotic Spindle
	Molecular Function	Receptor Activity Protein Binding
	Biological Process	Kidney Development Cellular Calcium Ion Homeostasis Positive Regulation Of Cell Proliferation Regulation Of Centrosome Duplication Single Organismal Cell-cell Adhesion Regulation Of TOR Signaling Negative Regulation Of NF-kappaB Transcription Factor Activity Cilium Assembly Homeostatic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cellular Component Movement Negative Regulation Of Protein Kinase B Signaling Regulation Of ERK1 And ERK2 Cascade
Pathways
Drugs
Diseases
GWAS		Prostate cancer ( 17903305) Waist circumference ( 19557197) Weight loss (gastric bypass surgery) ( 23633212)
Protein-protein Interactions		1 interactors: CAMLG
Entrez ID		5314
HPRD ID		05987
Ensembl ID		ENSG00000170927
Uniprot IDs		P08F94
PDB IDs
Enriched GO Terms of Interacting Partners?		Receptor Recycling Receptor Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway
Tagcloud ?		abca1 adamtsl3 aiming apc crc elac1 epha3 ephb6 ercc6 excluding exome fbxw7 germline kbiosciences marginal mll3 obscn recessive rs4987622 rs6464211 rs6947538 silico smad4 snps somatic spite strongest syne1 trpv6