OPHN1

Gene Name		oligophrenin 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Actin Cytoskeleton Cell Junction Terminal Bouton Dendritic Spine
	Molecular Function	Actin Binding Rho GTPase Activator Activity Phospholipid Binding Ionotropic Glutamate Receptor Binding
	Biological Process	Substrate-dependent Cell Migration, Cell Extension Signal Transduction Small GTPase Mediated Signal Transduction Nervous System Development Axon Guidance Actin Cytoskeleton Organization Regulation Of Endocytosis Positive Regulation Of Rho GTPase Activity Synaptic Vesicle Endocytosis Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Synaptic Transmission, Glutamatergic Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways		Rho GTPase cycle Signaling by Rho GTPases
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: CDC42 RAC1 RHOA
Entrez ID		4983
HPRD ID		02130
Ensembl ID		ENSG00000079482
Uniprot IDs		F5H2E3 O60890
PDB IDs
Enriched GO Terms of Interacting Partners?		Ephrin Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Cell-cell Junction Organization Positive Regulation Of Cell Projection Organization Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Phosphatidylinositol 3-kinase Activity Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Axon Guidance Regulation Of Substrate Adhesion-dependent Cell Spreading Blood Coagulation Hemostasis Substantia Nigra Development Positive Regulation Of Cytokinesis Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization Regulation Of Cytoskeleton Organization Positive Regulation Of Cell Development Positive Regulation Of Stress Fiber Assembly Axonogenesis Positive Regulation Of Actin Filament Bundle Assembly Regulation Of Phosphatidylinositol 3-kinase Activity Axon Development Regulation Of Body Fluid Levels Neural Nucleus Development Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Chemotaxis Actin Cytoskeleton Organization Regulation Of Cytokinesis Regulation Of Lipid Kinase Activity Small GTPase Mediated Signal Transduction Neuron Projection Morphogenesis Actin Filament-based Process Regulation Of Stress Fiber Assembly Positive Regulation Of DNA Replication Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Response To Wounding Cell Morphogenesis Involved In Differentiation T Cell Costimulation Regulation Of Small GTPase Mediated Signal Transduction Brain Development Midbrain Development Head Development Positive Regulation Of Intracellular Signal Transduction Neuron Projection Development Cell Migration Cell Projection Morphogenesis Regulation Of Cell Development Positive Regulation Of Cell Differentiation
Tagcloud ?		adhesion ampicillin biochemical biomarkers cast encodes escherichia fiber fibronectin gleason immunohistochemical immunohistochemistry interference interfering itga5 link lncap mental neither oligophrenin pc3 pca perform retardation si sirna transfected upregulated worse