NPR2

Gene Name		natriuretic peptide receptor 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Guanylate Cyclase Activity Protein Kinase Activity Receptor Activity Transmembrane Signaling Receptor Activity ATP Binding GTP Binding Natriuretic Peptide Receptor Activity Peptide Hormone Binding Hormone Binding Identical Protein Binding
	Biological Process	Ossification CGMP Biosynthetic Process Protein Phosphorylation Signal Transduction Cell Surface Receptor Signaling Pathway Receptor Guanylyl Cyclase Signaling Pathway Regulation Of Blood Pressure Intracellular Signal Transduction Single Organism Reproductive Process Negative Regulation Of Meiotic Cell Cycle Bone Development Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Negative Regulation Of Oocyte Maturation
Pathways
Drugs		Erythrityl Tetranitrate Nesiritide
Diseases
GWAS
Protein-protein Interactions		3 interactors: NPPA NPPB NPPC
Entrez ID		4882
HPRD ID		00166
Ensembl ID		ENSG00000159899
Uniprot IDs		P20594
PDB IDs
Enriched GO Terms of Interacting Partners?		Receptor Guanylyl Cyclase Signaling Pathway CGMP Biosynthetic Process CGMP Metabolic Process Cyclic Purine Nucleotide Metabolic Process Cyclic Nucleotide Biosynthetic Process Regulation Of Blood Vessel Size Regulation Of Tube Size Cyclic Nucleotide Metabolic Process Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Ribonucleotide Metabolic Process Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Blood Circulation Ribose Phosphate Metabolic Process Regulation Of Vasodilation Nucleotide Metabolic Process Regulation Of Growth Nucleobase-containing Small Molecule Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Organophosphate Metabolic Process Negative Regulation Of Cell Growth Regulation Of Blood Pressure Growth Plate Cartilage Chondrocyte Proliferation Negative Regulation Of Growth Negative Regulation Of Oocyte Maturation Response To Hypoxia Regulation Of Generation Of L-type Calcium Current Positive Regulation Of Delayed Rectifier Potassium Channel Activity Negative Regulation Of Oocyte Development Regulation Of Cell Growth Regulation Of Atrial Cardiac Muscle Cell Membrane Repolarization Regulation Of High Voltage-gated Calcium Channel Activity Positive Regulation Of Cardiac Muscle Contraction Growth Plate Cartilage Chondrocyte Differentiation Small Molecule Metabolic Process Regulation Of Delayed Rectifier Potassium Channel Activity Response To Muscle Stretch Positive Regulation Of Striated Muscle Contraction Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Renal Sodium Excretion Phosphate-containing Compound Metabolic Process Positive Regulation Of Urine Volume Positive Regulation Of Potassium Ion Transmembrane Transport Positive Regulation Of CGMP Biosynthetic Process Cardiac Muscle Hypertrophy In Response To Stress Chondrocyte Differentiation Involved In Endochondral Bone Morphogenesis Cell Surface Receptor Signaling Pathway Positive Regulation Of CGMP Metabolic Process Growth Plate Cartilage Development
Tagcloud ?		cat1 clearly deltanpr2 deltatsc2 discovered displayed feedback homeostasis isolating isp5 loop mislocalization negatively nutrient permease phenocopy phenotypes pombe rapamycin regulators schizosaccharomyces screen sensing supersensitivity terms tor tor2 torc1 tsc2