NDUFS1

Gene Name		NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Intermembrane Space
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity Electron Carrier Activity Metal Ion Binding 2 Iron, 2 Sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Apoptotic Mitochondrial Changes Respiratory Electron Transport Chain Cellular Metabolic Process Small Molecule Metabolic Process Cellular Respiration ATP Metabolic Process Regulation Of Mitochondrial Membrane Potential Reactive Oxygen Species Metabolic Process
Pathways		Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. Respiratory electron transport The citric acid (TCA) cycle and respiratory electron transport
Drugs		NADH
Diseases
GWAS
Protein-protein Interactions		3 interactors: CASP3 KDM1A MDH2
Entrez ID		4719
HPRD ID		01145
Ensembl ID
Uniprot IDs		E5KRK5 P28331
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Primitive Erythrocyte Differentiation Myeloid Cell Differentiation Glial Cell Apoptotic Process Regulation Of Apoptotic DNA Fragmentation Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Activated T Cell Proliferation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator NADH Metabolic Process Oxaloacetate Metabolic Process Malate Metabolic Process Granulocyte Differentiation Hemopoiesis Negative Regulation Of B Cell Proliferation Regulation Of Megakaryocyte Differentiation Apoptotic DNA Fragmentation Negative Regulation Of Histone Methylation Response To Wounding Positive Regulation Of Erythrocyte Differentiation Immune System Development Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Platelet Formation Platelet Morphogenesis Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Regulation Of Histone H3-K4 Methylation Regulation Of Execution Phase Of Apoptosis Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Hormone Biosynthetic Process Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Cellular Protein Metabolic Process Hippo Signaling Apoptotic Nuclear Changes Release Of Cytochrome C From Mitochondria Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Protein Metabolic Process Regulation Of Hormone Metabolic Process Histone Lysine Demethylation Negative Regulation Of Apoptotic Process Histone Demethylation Negative Regulation Of Programmed Cell Death Regulation Of Erythrocyte Differentiation
Tagcloud ?		acantholysis anxa8l1 atp2c1 blistering c5a cd1b cd32 cd88 cdh8 cdh9 chrm3 chrnd chrne col21a1 cyb5b desmoglein dra dsc1 dsc3 gp1ba justifies mucocutaneous multiplexed pdha1 pemphigus pkp3 pmp22 slc36a4 sod2