MMP15

Gene Name		matrix metallopeptidase 15 (membrane-inserted)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Extracellular Matrix
	Molecular Function	Metalloendopeptidase Activity Calcium Ion Binding Protein Binding Enzyme Activator Activity Zinc Ion Binding
	Biological Process	Cellular Protein Modification Process Proteolysis Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process Response To Estradiol Endodermal Cell Differentiation Positive Regulation Of Catalytic Activity
Pathways		Collagen degradation Activation of Matrix Metalloproteinases Degradation of the extracellular matrix
Drugs
Diseases
GWAS		Pulmonary function ( 21946350) Pulmonary function (interaction) ( 23284291)
Protein-protein Interactions		1 interactors: LRP1
Entrez ID		4324
HPRD ID		03775
Ensembl ID		ENSG00000102996
Uniprot IDs		P51511
PDB IDs
Enriched GO Terms of Interacting Partners?		Beta-amyloid Clearance Negative Regulation Of Platelet-derived Growth Factor Receptor-beta Signaling Pathway Regulation Of Phospholipase A2 Activity Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Negative Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Cholesterol Efflux Positive Regulation Of Cholesterol Transport Lipoprotein Transport Regulation Of Cholesterol Efflux Aorta Morphogenesis Aorta Development Apoptotic Cell Clearance Regulation Of Cholesterol Transport Regulation Of Smooth Muscle Cell Migration Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway Artery Morphogenesis Positive Regulation Of Lipid Transport Artery Development Phototransduction, Visible Light Retinoid Metabolic Process Regulation Of Phospholipase Activity Diterpenoid Metabolic Process Detection Of Visible Light Regulation Of Lipid Transport Phototransduction Detection Of Light Stimulus Cholesterol Metabolic Process Isoprenoid Metabolic Process Sterol Metabolic Process Lipoprotein Metabolic Process Detection Of Abiotic Stimulus Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Migration Negative Regulation Of Neuron Death Negative Regulation Of Cell Motility Negative Regulation Of Cellular Component Movement Regulation Of Neuron Apoptotic Process Negative Regulation Of Locomotion Steroid Metabolic Process Phagocytosis Regulation Of Neuron Death Regulation Of Wnt Signaling Pathway Aging Positive Regulation Of Protein Transport Response To Light Stimulus Alcohol Metabolic Process Receptor-mediated Endocytosis Regulation Of Actin Cytoskeleton Organization
Tagcloud ?		aldh1a1 amls carrying chemo clearance confers d835 dominated duplication effectors expanded flt3 fms immunodeficiency initiating itd jak3 leukemias lics myeloblasts nonobese recapitulated relapsed sorafenib subclones thirteen transplanted twelve twice