METTL1

Gene Name		methyltransferase like 1
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm TRNA Methyltransferase Complex
	Molecular Function	TRNA Binding Protein Binding TRNA (guanine-N7-)-methyltransferase Activity
	Biological Process	TRNA Modification TRNA Methylation RNA (guanine-N7)-methylation
Pathways
Drugs
Diseases
GWAS		Multiple sclerosis ( 19525955)
Protein-protein Interactions		3 interactors: AKT1 RPS6KA1 WDR4
Entrez ID		4234
HPRD ID		06834
Ensembl ID		ENSG00000037897
Uniprot IDs		Q9UBP6
PDB IDs		3CKK
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Cell Growth Glycogen Cell Differentiation Involved In Embryonic Placenta Development Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Cysteine-type Endopeptidase Activity Positive Regulation Of Hepatic Stellate Cell Activation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Growth Neurotrophin Signaling Pathway Negative Regulation Of Endopeptidase Activity Regulation Of Translation Negative Regulation Of Peptidase Activity Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Negative Regulation Of Fatty Acid Beta-oxidation Positive Regulation Of Cell Activation Regulation Of Cell Growth Negative Regulation Of Proteolysis RNA (guanine-N7)-methylation Response To UV-A Negative Regulation Of Protein Processing Regulation Of Endopeptidase Activity Activation-induced Cell Death Of T Cells Negative Regulation Of Hydrolase Activity Regulation Of Protein Processing Regulation Of Peptidase Activity Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Involved In G1/S Transition Of Mitotic Cell Cycle Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Posttranscriptional Regulation Of Gene Expression Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Negative Regulation Of Fatty Acid Oxidation Positive Regulation Of Glycogen Biosynthetic Process Nitric Oxide Biosynthetic Process Cellular Response To Growth Factor Stimulus Negative Regulation Of Cell Size Response To Growth Factor Regulation Of Translation In Response To Stress Regulation Of Growth Negative Regulation Of Release Of Cytochrome C From Mitochondria Spongiotrophoblast Layer Development T Cell Apoptotic Process Regulation Of Fatty Acid Beta-oxidation Negative Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Nitric-oxide Synthase Activity Regulation Of Proteolysis Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Blood Vessel Endothelial Cell Migration Insulin-like Growth Factor Receptor Signaling Pathway Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
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