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TRIM74
Gene Name
tripartite motif containing 74
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Intracellular
Molecular Function
Zinc Ion Binding
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions
11 interactors:
BRCA1
LRSAM1
MGRN1
RBX1
REL
RNF32
TSG101
UBE2U
USP15
USP2
USP32
Entrez ID
378108
HPRD ID
15567
Ensembl ID
ENSG00000155428
Uniprot IDs
Q86UV6
PDB IDs
Enriched GO Terms of Interacting Partners
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Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cellular Protein Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Protein Modification Process
Cellular Macromolecule Catabolic Process
Protein Polyubiquitination
Catabolic Process
Protein Ubiquitination
Cellular Protein Metabolic Process
Protein Modification By Small Protein Conjugation
Viral Budding
Protein Deubiquitination
Proteolysis
Protein Modification By Small Protein Removal
Protein Metabolic Process
Virion Assembly
Regulation Of Proteasomal Protein Catabolic Process
Protein Monoubiquitination
Protein Autoubiquitination
Cellular Metabolic Process
Positive Regulation Of Histone H4-K20 Methylation
Positive Regulation Of Histone H4-K16 Acetylation
Ubiquitin-dependent Endocytosis
Regulation Of Protein Catabolic Process
Membrane Budding
Regulation Of Transcription From RNA Polymerase II Promoter
Negative Regulation Of Signal Transduction
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Positive Regulation Of Histone H3-K9 Acetylation
Histone H2B Conserved C-terminal Lysine Deubiquitination
Negative Regulation Of RNA Biosynthetic Process
Negative Regulation Of Signaling
Regulation Of Protein Metabolic Process
Positive Regulation Of Histone H4 Acetylation
Negative Regulation Of Histone H3-K4 Methylation
Viral Process
Negative Regulation Of Gene Expression
DNA Repair
Negative Regulation Of Biosynthetic Process
Cellular Response To Indole-3-methanol
Regulation Of Proteolysis
Negative Regulation Of Centriole Replication
Regulation Of Extracellular Vesicular Exosome Assembly
Viral Life Cycle
Dosage Compensation By Inactivation Of X Chromosome
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