ITGAX

Gene Name		integrin, alpha X (complement component 3 receptor 4 subunit)
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integrin Complex Cell Surface Membrane
	Molecular Function	Receptor Activity Protein Binding Metal Ion Binding
	Biological Process	Cell Adhesion Integrin-mediated Signaling Pathway Blood Coagulation Organ Morphogenesis Extracellular Matrix Organization Heterotypic Cell-cell Adhesion Leukocyte Migration
Pathways		ECM proteoglycans Integrin cell surface interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Systemic lupus erythematosus ( 18204098)
Protein-protein Interactions		4 interactors: C3 FCER2 ITGB2 JAM3
Entrez ID		3687
HPRD ID		01051
Ensembl ID		ENSG00000140678
Uniprot IDs		H3BN02 P20702 Q8TES5
PDB IDs		1N3Y 2LUV 3K6S 3K71 3K72
Enriched GO Terms of Interacting Partners?		Leukocyte Migration Involved In Inflammatory Response Positive Regulation Of Humoral Immune Response Regulation Of Immune System Process Positive Regulation Of Immunoglobulin Mediated Immune Response Inflammatory Response Regulation Of Humoral Immune Response Positive Regulation Of Immune Response Positive Regulation Of Angiogenesis Regulation Of Actin Cytoskeleton Organization By Cell-cell Adhesion Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Adaptive Immune Response Cell-matrix Adhesion Positive Regulation Of Type IIa Hypersensitivity Regulation Of Adaptive Immune Response Cell-substrate Adhesion Regulation Of Angiogenesis Leukocyte Migration Positive Regulation Of Activation Of Membrane Attack Complex Immune Response Defense Response Adaptive Immune Response Positive Regulation Of Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Hypersensitivity Positive Regulation Of Apoptotic Cell Clearance Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Extracellular Matrix Organization Extracellular Structure Organization Myeloid Progenitor Cell Differentiation Positive Regulation Of Killing Of Cells Of Other Organism Regulation Of Killing Of Cells Of Other Organism Regulation Of Apoptotic Cell Clearance Blood Coagulation Hemostasis Complement Activation, Alternative Pathway Positive Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Cellular Component Organization Positive Regulation Of Nitric-oxide Synthase Biosynthetic Process Neutrophil Homeostasis Single Organismal Cell-cell Adhesion Immune System Process Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Nitric-oxide Synthase Activity Positive Regulation Of Protein Processing Regulation Of Triglyceride Biosynthetic Process Signaling Regulation Of Body Fluid Levels Cell Communication Wound Healing Heterotypic Cell-cell Adhesion
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