INPP5B

Gene Name		inositol polyphosphate-5-phosphatase, 75kDa
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Gene Ontology Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Plasma Membrane Membrane Integral Component Of Membrane Phagocytic Vesicle Membrane Early Endosome Membrane
	Molecular Function	Phosphatidylinositol-4,5-bisphosphate 5-phosphatase Activity Protein Binding Metal Ion Binding Inositol-1,4,5-trisphosphate 5-phosphatase Activity
	Biological Process	In Utero Embryonic Development Small GTPase Mediated Signal Transduction Spermatogenesis Sperm Motility Inositol Phosphate Metabolic Process Small Molecule Metabolic Process Phosphatidylinositol Dephosphorylation Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Protein Processing
Pathways		Rho GTPase cycle Synthesis of IP3 and IP4 in the cytosol Synthesis of IP2, IP, and Ins in the cytosol Signaling by Rho GTPases Inositol phosphate metabolism
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: APP SMURF1
Entrez ID		3633
HPRD ID		00924
Ensembl ID		ENSG00000204084
Uniprot IDs		P32019
PDB IDs		3MTC 3N9V
Enriched GO Terms of Interacting Partners?		Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Ubiquitin-dependent SMAD Protein Catabolic Process Neuron Remodeling Cellular Copper Ion Homeostasis Protein Localization To Cell Surface Receptor Catabolic Process Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Ectoderm Development Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Protein Export From Nucleus Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway Ionotropic Glutamate Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Intracellular Transport Axon Cargo Transport Mating Neuromuscular Junction Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Neuron Apoptotic Process Positive Regulation Of Cell Cycle Phase Transition Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Tyrosine Kinase Activity Visual Learning Glutamate Receptor Signaling Pathway Visual Behavior Neuron Death Platelet Degranulation Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Epidermal Growth Factor Receptor Signaling Pathway BMP Signaling Pathway Neuromuscular Process Controlling Balance Synapse Assembly Negative Regulation Of Ossification MRNA 3'-end Processing
Tagcloud ?		actin comet cr3 detached detaches detachment dissociates drives endomembranes engulf integrins nascent phagocytic phagosomal phagosomes phosphatidylinositide phosphoinositide pi pi3ks polymerization polymerized propel pseudopods sealed seals tails vacuole vacuoles waves