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IL3RA
Gene Name
interleukin 3 receptor, alpha (low affinity)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Membrane
Molecular Function
Interleukin-3 Receptor Activity
Biological Process
Cellular Response To Interleukin-3
Interleukin-3-mediated Signaling Pathway
Pathways
Signaling by GPCR
G-protein beta:gamma signalling
Cytokine Signaling in Immune system
GPCR downstream signaling
Signaling by Interleukins
Interleukin receptor SHC signaling
G beta:gamma signalling through PI3Kgamma
Interleukin receptor SHC signaling
GPVI-mediated activation cascade
Interleukin-2 signaling
Platelet activation, signaling and aggregation
Interleukin-3, 5 and GM-CSF signaling
Drugs
Sargramostim
Diseases
GWAS
Schizophrenia (
17522711
)
Protein-protein Interactions
15 interactors:
CDC25A
CDK1
CISH
CSF2
CSF2RB
FOXP1
GNA12
IL3
JAK1
JAK2
LNX1
NR0B2
PPP1CC
SAE1
SGK2
Entrez ID
3563
HPRD ID
02392
Ensembl ID
ENSG00000185291
Uniprot IDs
P26951
PDB IDs
Enriched GO Terms of Interacting Partners
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Positive Regulation Of Tyrosine Phosphorylation Of Stat5 Protein
Regulation Of JAK-STAT Cascade
Response To Organic Substance
Cellular Response To Organic Substance
Regulation Of Signaling
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Cytokine-mediated Signaling Pathway
Positive Regulation Of JAK-STAT Cascade
Positive Regulation Of DNA Replication
Regulation Of Signal Transduction
Regulation Of Cell Proliferation
Cellular Response To Cytokine Stimulus
Positive Regulation Of Protein Import Into Nucleus, Translocation
Regulation Of Protein Phosphorylation
Cellular Protein Modification Process
Response To Lipopolysaccharide
Cellular Response To Stimulus
Response To Molecule Of Bacterial Origin
Response To Stimulus
Response To Cytokine
Regulation Of Protein Import Into Nucleus, Translocation
Regulation Of DNA Replication
Immune Response
Regulation Of Interferon-gamma-mediated Signaling Pathway
Regulation Of Phosphorylation
Regulation Of Cellular Protein Metabolic Process
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Regulation Of Response To Interferon-gamma
Positive Regulation Of DNA Metabolic Process
Positive Regulation Of Cell Proliferation
Growth Hormone Receptor Signaling Pathway
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Response To Lipid
Cellular Response To Growth Hormone Stimulus
Enzyme Linked Receptor Protein Signaling Pathway
Macrophage Activation
Regulation Of Phosphorus Metabolic Process
Response To Toxic Substance
Regulation Of Protein Metabolic Process
Response To Bacterium
Cell Surface Receptor Signaling Pathway
Signal Transduction
Peptidyl-tyrosine Autophosphorylation
Regulation Of Peptidyl-tyrosine Phosphorylation
Response To Growth Hormone
Histone Phosphorylation
Regulation Of Cardiac Muscle Cell Proliferation
Cellular Protein Metabolic Process
Cellular Response To Hormone Stimulus
Regulation Of Intracellular Signal Transduction
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bioinformatics
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pathohistological
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