IDH2

Gene Name		isocitrate dehydrogenase 2 (NADP+), mitochondrial
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Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Isocitrate Dehydrogenase (NADP+) Activity NAD Binding
	Biological Process	Carbohydrate Metabolic Process Glyoxylate Cycle Tricarboxylic Acid Cycle Isocitrate Metabolic Process 2-oxoglutarate Metabolic Process Cellular Metabolic Process Small Molecule Metabolic Process
Pathways		Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Citric acid cycle (TCA cycle)
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: PYGL SLC2A4
Entrez ID		3418
HPRD ID		00973
Ensembl ID		ENSG00000182054
Uniprot IDs		B4DFL2 B4DSZ6 P48735
PDB IDs		4JA8
Enriched GO Terms of Interacting Partners?		Glucose Homeostasis Pathogenesis Amylopectin Biosynthetic Process 5-phosphoribose 1-diphosphate Biosynthetic Process Glucose Import Chemical Homeostasis Glycogen Catabolic Process Polysaccharide Catabolic Process Carbohydrate Metabolic Process Hexose Transmembrane Transport Cellular Response To Osmotic Stress Cellular Carbohydrate Catabolic Process Necroptotic Process Homeostatic Process Brown Fat Cell Differentiation Programmed Necrotic Cell Death Necrotic Cell Death Carbohydrate Transmembrane Transport Glycogen Metabolic Process Glucose Transport Hexose Transport Polysaccharide Metabolic Process Response To Osmotic Stress Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Small Molecule Metabolic Process Carbohydrate Transport Fat Cell Differentiation Energy Reserve Metabolic Process Response To Ethanol Glucose Metabolic Process Carbohydrate Catabolic Process Ribose Phosphate Biosynthetic Process Hexose Metabolic Process Cellular Response To Insulin Stimulus Cellular Carbohydrate Metabolic Process Monosaccharide Metabolic Process Response To Insulin Response To Hypoxia Energy Derivation By Oxidation Of Organic Compounds Cellular Response To Peptide Hormone Stimulus Ribose Phosphate Metabolic Process Cellular Response To Peptide
Tagcloud ?		abstract advancements ascribed asxl1 attitude azacitidine challenging changing choices conditioning curative decitabine feasible haploidentical hematologists hypomethylating incurable optimize overview profoundly renders sf3b1 sibling spite stratify tet2 transplant video wider