HOXD8

Gene Name		homeobox D8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Anterior/posterior Axis Specification, Embryo Positive Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Morphogenesis
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: ANXA7 CDKN1A HMGB1 PFDN1 RCC1
Entrez ID		3234
HPRD ID		00868
Ensembl ID		ENSG00000175879
Uniprot IDs		F8VSA3 P13378
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Apoptotic Cell Clearance Regulation Of Cellular Component Organization Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Base-excision Repair, DNA Ligation Intestinal Epithelial Cell Maturation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cellular Response To UV-B Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Negative Regulation Of Gene Expression Cell Cycle Positive Regulation Of Ran GTPase Activity DNA Ligation Involved In DNA Repair Stress-induced Premature Senescence Regulation Of Apoptotic Cell Clearance Negative Regulation Of Phagocytosis Positive Regulation Of Catalytic Activity Cellular Water Homeostasis Regulation Of Mitotic Cell Cycle DNA Ligation Dendritic Cell Chemotaxis Regulation Of Metabolic Process Mitotic Cell Cycle Arrest Response To UV-B Intestinal Epithelial Cell Development Regulation Of Protein Import Into Nucleus, Translocation Apoptotic DNA Fragmentation Leukocyte Activation Regulation Of Cell Cycle Process Intestinal Epithelial Cell Differentiation Epithelial Cell Maturation Regulation Of DNA-templated Transcription, Initiation Epithelial Cell Differentiation Dendritic Cell Migration Response To Arsenic-containing Substance Myeloid Dendritic Cell Activation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Chemotaxis Positive Regulation Of Programmed Cell Death V(D)J Recombination Cellular Senescence Positive Regulation Of Cell Death Apoptotic Nuclear Changes Cell Volume Homeostasis Immune System Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray
Tagcloud ?		chip deep dysregulated dysregulation h3k27me3 homeobox hoxb7 hoxc10 hoxc13 irx1 irx4 keratinocytes mark neoplastic okf6 oncomine polycomb prc prc2 repressive rnaseq scc six2 suz12 tert1r transcripts tshz3 tumorigenic