HLA-DRB3

Gene Name		major histocompatibility complex, class II, DR beta 3
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Gene Ontology Annotations	Cellular Component	Golgi Membrane Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Late Endosome Membrane Trans-Golgi Network Membrane MHC Class II Protein Complex Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane
	Molecular Function	Protein Binding MHC Class II Receptor Activity Peptide Antigen Binding
	Biological Process	Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response Inflammatory Response To Antigenic Stimulus Humoral Immune Response Mediated By Circulating Immunoglobulin Immune Response Signal Transduction Detection Of Bacterium Cytokine-mediated Signaling Pathway Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II T Cell Costimulation Regulation Of Interleukin-4 Production Negative Regulation Of Interferon-gamma Production Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus T-helper 1 Type Immune Response Negative Regulation Of T Cell Proliferation T Cell Receptor Signaling Pathway Protein Tetramerization Interferon-gamma-mediated Signaling Pathway Regulation Of Interleukin-10 Secretion
Pathways		Generation of second messenger molecules Downstream TCR signaling Costimulation by the CD28 family Translocation of ZAP-70 to Immunological synapse Interferon Signaling Cytokine Signaling in Immune system Interferon gamma signaling TCR signaling MHC class II antigen presentation PD-1 signaling Phosphorylation of CD3 and TCR zeta chains Adaptive Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: CDCA8 CTAG1B MAP3K13 POMC
Entrez ID		3125
HPRD ID		09985
Ensembl ID
Uniprot IDs		P79483
PDB IDs		2Q6W 3C5J 4H1L
Enriched GO Terms of Interacting Partners?
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