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HADHB
Gene Name
hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Mitochondrion
Mitochondrial Envelope
Mitochondrial Outer Membrane
Mitochondrial Inner Membrane
Endoplasmic Reticulum
Mitochondrial Fatty Acid Beta-oxidation Multienzyme Complex
Mitochondrial Nucleoid
Extracellular Vesicular Exosome
Molecular Function
Fatty-acyl-CoA Binding
3-hydroxyacyl-CoA Dehydrogenase Activity
Acetyl-CoA C-acyltransferase Activity
Enoyl-CoA Hydratase Activity
Protein Binding
Long-chain-enoyl-CoA Hydratase Activity
Long-chain-3-hydroxyacyl-CoA Dehydrogenase Activity
Protein Complex Binding
Poly(A) RNA Binding
NAD Binding
Biological Process
Fatty Acid Beta-oxidation
Phospholipid Metabolic Process
Cardiolipin Acyl-chain Remodeling
Cellular Lipid Metabolic Process
Small Molecule Metabolic Process
Glycerophospholipid Biosynthetic Process
Pathways
Acyl chain remodeling of CL
Fatty acid, triacylglycerol, and ketone body metabolism
Metabolism of lipids and lipoproteins
Mitochondrial Fatty Acid Beta-Oxidation
Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA
Glycerophospholipid biosynthesis
Beta oxidation of hexanoyl-CoA to butanoyl-CoA
Beta oxidation of palmitoyl-CoA to myristoyl-CoA
Beta oxidation of octanoyl-CoA to hexanoyl-CoA
Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA
mitochondrial fatty acid beta-oxidation of saturated fatty acids
Beta oxidation of myristoyl-CoA to lauroyl-CoA
Phospholipid metabolism
Drugs
Diseases
GWAS
Protein-protein Interactions
12 interactors:
ANXA7
APP
CDKN1A
CHCHD4
COX17
GRB7
RCC1
SMN1
SUOX
TIMM8B
TK1
TNNI3K
Entrez ID
3032
HPRD ID
00887
Ensembl ID
ENSG00000138029
Uniprot IDs
B4E2W0
F5GZQ3
P55084
PDB IDs
Enriched GO Terms of Interacting Partners
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Protein Targeting To Mitochondrion
Protein Import Into Mitochondrial Intermembrane Space
Fetal Process Involved In Parturition
Protein Localization To Mitochondrion
Regulation Of Mitotic Cell Cycle
Skeletal Muscle Cell Proliferation
Synaptic Growth At Neuromuscular Junction
Hemostasis
Collateral Sprouting In Absence Of Injury
Cellular Component Assembly
Regulation Of Cell Cycle Process
Digestive Tract Development
Collateral Sprouting
Axon Midline Choice Point Recognition
Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase
Intestinal Epithelial Cell Maturation
Cell Maturation
Digestive System Development
Regulation Of Body Fluid Levels
Mitochondrial Transport
Response To Glucocorticoid
G1/S Transition Of Mitotic Cell Cycle
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Response To Cortisol
Thymidine Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Response To Corticosteroid
Ribonucleoprotein Complex Assembly
Axon Choice Point Recognition
Response To Toxic Substance
Cellular Response To UV-B
Chaperone-mediated Protein Transport
Deoxyribonucleoside Monophosphate Biosynthetic Process
Positive Regulation Of Ran GTPase Activity
Neuron Remodeling
Pyrimidine Nucleoside Salvage
Pyrimidine-containing Compound Salvage
Cellular Metabolic Process
Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Process
Stress-induced Premature Senescence
Protein Maturation By Protein Folding
Regulation Of Cell Cycle Phase Transition
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