LRP12

Gene Name		low density lipoprotein receptor-related protein 12
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Coated Pit Integral Component Of Membrane
	Molecular Function	Low-density Lipoprotein Receptor Activity Protein Binding
	Biological Process	Endocytosis Receptor-mediated Endocytosis Signal Transduction Regulation Of Growth
Pathways		Visual phototransduction Diseases associated with visual transduction Retinoid metabolism and transport
Drugs
Diseases
GWAS		Glaucoma (primary open-angle) ( 22570617) Vascular endothelial growth factor levels ( 21757650)
Protein-protein Interactions		6 interactors: ACTN2 GNB2L1 MYOT NMRK2 SNAPIN ZFYVE9
Entrez ID		29967
HPRD ID		17447
Ensembl ID		ENSG00000147650
Uniprot IDs		Q59H02 Q9Y561
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Late Endosome To Lysosome Transport Positive Regulation Of CAMP Catabolic Process Terminal Button Organization Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Autophagic Vacuole Maturation Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Muscle Contraction Microspike Assembly Regulation Of Cellular Localization Negative Regulation Of Oxidative Stress-induced Neuron Death Muscle System Process Negative Regulation Of Protein Localization To Cell Surface SMAD Protein Import Into Nucleus Positive Regulation Of Protein Homooligomerization Positive Regulation Of Gastrulation Negative Regulation Of Hydrogen Peroxide-induced Cell Death Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Mitochondrial Depolarization Synaptic Vesicle Fusion To Presynaptic Membrane Exocytosis Regulation Of Hydrogen Peroxide-induced Cell Death SMAD Protein Complex Assembly Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Negative Regulation Of Phagocytosis Synaptic Vesicle Maturation Negative Regulation Of Potassium Ion Transmembrane Transport Vesicle-mediated Transport Negative Regulation Of Transport Positive Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Mitochondrial Depolarization Positive Regulation Of Protein Oligomerization Regulation Of Protein Localization To Cell Surface Anterograde Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Negative Regulation Of Potassium Ion Transport Negative Regulation Of Myoblast Differentiation Secretion By Cell Negative Regulation Of Oxidative Stress-induced Cell Death Regulation Of Protein Oligomerization Regulation Of Potassium Ion Transmembrane Transporter Activity Anterograde Axon Cargo Transport NAD Biosynthetic Process Regulation Of Response To Reactive Oxygen Species Positive Regulation Of Potassium Ion Transport Viral Process Endosome To Lysosome Transport Positive Regulation Of Embryonic Development Actin-myosin Filament Sliding
Tagcloud ?		as1 atoh7 beadchip cav1 cav2 cdkn2b cnvs cyp1b1 duplications fndc3b galc gas7 glaugen human660w interrogated kilobases merit myoc neighbor optn penncnv poag quad six1 six6 srbd1 tmco1 wdr36 zfpm2