SUMF2

Gene Name		sulfatase modifying factor 2
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Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Lumen
	Molecular Function	Metal Ion Binding
	Biological Process	Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Sphingolipid metabolism Metabolism of lipids and lipoproteins Glycosphingolipid metabolism Post-translational protein modification The activation of arylsulfatases Gamma carboxylation, hypusine formation and arylsulfatase activation
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: CACNA1A FBXW7 ZDHHC17 ZFYVE9
Entrez ID		25870
HPRD ID		06400
Ensembl ID		ENSG00000129103
Uniprot IDs		Q8NBJ7
PDB IDs		1Y4J
Enriched GO Terms of Interacting Partners?		Cerebellar Molecular Layer Development Negative Regulation Of SREBP Signaling Pathway Regulation Of Signaling Negative Regulation Of Triglyceride Biosynthetic Process Vestibular Nucleus Development Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cerebellum Maturation Musculoskeletal Movement, Spinal Reflex Action Regulation Of Neuron Apoptotic Process Negative Regulation Of Hepatocyte Proliferation Gamma-aminobutyric Acid Secretion Negative Regulation Of DNA Endoreduplication Regulation Of Acetylcholine Secretion, Neurotransmission Regulation Of Neuron Death Rhythmic Synaptic Transmission Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Oxidative Stress-induced Cell Death Calcium Ion-dependent Exocytosis Of Neurotransmitter Cellular Chloride Ion Homeostasis SMAD Protein Import Into Nucleus Gamma-aminobutyric Acid Transport Chloride Ion Homeostasis Regulation Of DNA Endoreduplication Regulation Of Hepatocyte Proliferation Negative Regulation Of Hormone Biosynthetic Process Positive Regulation Of Epidermal Growth Factor-activated Receptor Activity Pons Development SMAD Protein Complex Assembly Protein Localization Signal Transduction Cerebellar Purkinje Cell Differentiation Cerebellar Purkinje Cell Layer Morphogenesis Regulation Of Triglyceride Biosynthetic Process Signaling Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Lipoprotein Transport Magnesium Ion Transport Cell Communication Reflex Behavioral Response To Pain Positive Regulation Of ERBB Signaling Pathway Neuromuscular Synaptic Transmission SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Hormone Biosynthetic Process Cerebellar Cortex Formation Neurotransmitter Metabolic Process Regulation Of Epidermal Growth Factor-activated Receptor Activity Sister Chromatid Cohesion Protein Palmitoylation
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