PAN3

Gene Name		PAN3 poly(A) specific ribonuclease subunit
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Cytosol PAN Complex
	Molecular Function	Poly(A)-specific Ribonuclease Activity Protein Binding ATP Binding Transferase Activity, Transferring Phosphorus-containing Groups Metal Ion Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Poly(A) Tail Shortening Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Protein Targeting Gene Expression Positive Regulation Of Cytoplasmic MRNA Processing Body Assembly RNA Phosphodiester Bond Hydrolysis, Exonucleolytic
Pathways		Deadenylation of mRNA Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: PABPC1 PAN2 SVIL
Entrez ID		255967
HPRD ID		17818
Ensembl ID		ENSG00000152520
Uniprot IDs		Q58A45
PDB IDs
Enriched GO Terms of Interacting Partners?		Nuclear-transcribed MRNA Poly(A) Tail Shortening Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay MRNA 3'-end Processing RNA 3'-end Processing Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Processing Aromatic Compound Catabolic Process Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening MRNA Metabolic Process RNA Processing Positive Regulation Of MRNA 3'-end Processing Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Regulation Of MRNA 3'-end Processing Positive Regulation Of MRNA Catabolic Process MRNA Stabilization MRNA Polyadenylation RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Cellular Macromolecule Catabolic Process RNA Polyadenylation Positive Regulation Of Cytokinesis Regulation Of MRNA Stability Regulation Of RNA Stability Regulation Of Cytokinesis Gene Silencing By RNA Positive Regulation Of Translation Positive Regulation Of Type I Interferon Production Regulation Of MRNA Processing Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Gene Silencing Regulation Of Type I Interferon Production RNA Phosphodiester Bond Hydrolysis Positive Regulation Of Cell Division Catabolic Process Skeletal Muscle Tissue Development Osteoblast Differentiation Skeletal Muscle Organ Development
Tagcloud ?		anchoring architecture asymmetric cerevisiae deadenylase deadenylate deadenylation homodimer hydrolase imparted intertwined latches module needing nuclease onto orient pab1 pan2 pseudokinase pseudoubiquitin rnase saccharomyces shortening stoichiometry synergy tails unusual wraps