POFUT1

Gene Name		protein O-fucosyltransferase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane
	Molecular Function	Fucosyltransferase Activity Peptide-O-fucosyltransferase Activity
	Biological Process	Angiogenesis Somitogenesis Fucose Metabolic Process Regulation Of Transcription, DNA-templated Protein O-linked Glycosylation Notch Signaling Pathway Nervous System Development Heart Development Embryo Development O-glycan Processing Protein O-linked Fucosylation
Pathways		Signaling by NOTCH Pre-NOTCH Processing in the Endoplasmic Reticulum Pre-NOTCH Expression and Processing
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: AKT2 DLL1 JAG1 NOTCH1
Entrez ID		23509
HPRD ID		06319
Ensembl ID		ENSG00000101346
Uniprot IDs		Q9H488
PDB IDs
Enriched GO Terms of Interacting Partners?		Notch Receptor Processing Neuronal Stem Cell Maintenance Compartment Pattern Specification Renal Tubule Development Notch Signaling Involved In Heart Development Pulmonary Valve Morphogenesis Notch Signaling Pathway Nephron Development Stem Cell Maintenance Kidney Epithelium Development Loop Of Henle Development Distal Tubule Development Left/right Axis Specification Inner Ear Development Negative Regulation Of Neuron Differentiation Heart Morphogenesis Response To Muramyl Dipeptide Ear Development Cardiac Right Ventricle Morphogenesis Epithelium Development Stem Cell Development Left/right Pattern Formation Negative Regulation Of Neurogenesis Positive Regulation Of Notch Signaling Pathway Cell Fate Commitment Kidney Development Stem Cell Differentiation Auditory Receptor Cell Differentiation Renal System Development Negative Regulation Of Cell Development Negative Regulation Of Stem Cell Differentiation Heart Valve Morphogenesis Heart Valve Development Hair Cell Differentiation Endocardial Cushion Development Urogenital System Development Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Epidermal Cell Differentiation Myoblast Differentiation Positive Regulation Of Cellular Biosynthetic Process Neurogenesis Cell Fate Determination Tissue Development Response To Peptide Artery Morphogenesis Cardiac Septum Morphogenesis Cell Development Inner Ear Receptor Cell Differentiation Heart Looping Morphogenesis Of An Epithelium
Tagcloud ?		advances chaperone consensus contexts discusses distinguish folded folding fucosylates fucosylation fucosyltransferase glycosylation glycosyltransferases metazoans modifies modify notably notch participate proper repeats though thrombospondin tsr tsrs unfolded