USP12

Gene Name		ubiquitin specific peptidase 12
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component
	Molecular Function	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Protein Deubiquitination
Pathways
Drugs
Diseases
GWAS		Alcohol dependence ( 21314694) Ulcerative colitis ( 19915573)
Protein-protein Interactions		5 interactors: APP HIST2H2AC HIST2H2BE NOTCH1 UBC
Entrez ID		219333
HPRD ID		15631
Ensembl ID		ENSG00000152484
Uniprot IDs		O75317
PDB IDs
Enriched GO Terms of Interacting Partners?		Notch Signaling Pathway Notch Receptor Processing Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Immune Response Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Defense Response Regulation Of DNA-templated Transcription In Response To Stress Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Venous Endothelial Cell Differentiation Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Cellular Response To Oxygen Levels Immune System Process Negative Regulation Of Catalytic Activity Developmental Growth Involved In Morphogenesis Innate Immune Response Negative Regulation Of Canonical Wnt Signaling Pathway Vasculogenesis Involved In Coronary Vascular Morphogenesis Synaptic Growth At Neuromuscular Junction Cardiac Right Atrium Morphogenesis Mitral Valve Formation Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Negative Regulation Of Pro-B Cell Differentiation Growth Involved In Heart Morphogenesis Atrioventricular Node Development Collateral Sprouting In Absence Of Injury Coronary Vein Morphogenesis Apoptotic Process Negative Regulation Of Neuron Differentiation Negative Regulation Of Wnt Signaling Pathway Intracellular Receptor Signaling Pathway Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Cell Migration Involved In Endocardial Cushion Formation Cardiac Right Ventricle Formation Negative Regulation Of Endothelial Cell Chemotaxis Negative Regulation Of Photoreceptor Cell Differentiation Cell Death Death Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Regulation Of Canonical Wnt Signaling Pathway DNA-templated Transcription, Initiation Response To Abiotic Stimulus
Tagcloud ?		androgen ar chip cofactors deubiquitinates deubiquitinating deubiquitination e3 enhancing enzymatic enzymes equally hence impacts interplay ligases mdm2 nedd4 offer prostate protease proteosomal screen stabilizing uaf ubiquitin ubiquitinated ubiquitination wdr20