ENO1

Gene Name		enolase 1, (alpha)
Image
Gene Ontology Annotations	Cellular Component	Phosphopyruvate Hydratase Complex Extracellular Space Nucleus Cytoplasm Cytosol Plasma Membrane Membrane M Band Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Phosphopyruvate Hydratase Activity Protein Binding Poly(A) RNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Transcription, DNA-templated Pathogenesis Response To Virus Negative Regulation Of Cell Growth Small Molecule Metabolic Process Negative Regulation Of Transcription, DNA-templated
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs
Diseases
GWAS		Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885)
Protein-protein Interactions		20 interactors: AGTPBP1 AMBP BHLHE40 BRCA1 FANCA FYN GRB2 HDAC1 LIG4 MYOC PCNA PLG SERPING1 SRC SUMO4 TERT TRAPPC2 UPF2 YWHAQ YWHAZ
Entrez ID		2023
HPRD ID		01400
Ensembl ID		ENSG00000074800
Uniprot IDs		E2DRY6 P06733
PDB IDs		2PSN 3B97
Enriched GO Terms of Interacting Partners?		Platelet Activation Blood Coagulation Hemostasis Developmental Process Regulation Of Body Fluid Levels Wound Healing Positive Regulation Of Organelle Organization Organ Development Cell Activation Response To Wounding Negative Regulation Of Signal Transduction Multicellular Organismal Development DNA Strand Elongation Negative Regulation Of Signaling Anatomical Structure Development System Development Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Viral Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Cell Death ERBB Signaling Pathway Vesicle-mediated Transport Negative Regulation Of Cell-substrate Adhesion Regulation Of Apoptotic Process Regulation Of Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway Response To Stress Regulation Of Signal Transduction Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Leukocyte Migration T Cell Costimulation Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Positive Regulation Of Signal Transduction Negative Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Gene Expression Regulation Of Signaling DNA Replication Regulation Of Organelle Organization Nucleotide-excision Repair, DNA Gap Filling Regulation Of Mitochondrial Depolarization DNA Biosynthetic Process Cellular Metabolic Process Regulation Of Cell Proliferation Regulation Of Cell Adhesion Postreplication Repair Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
Tagcloud ?		assigned carrying cell cells chromosome chromosomes electrophoresis enolase equilibrium expression gel gene human hybrids indicated mouse p36 pter reciprocal region results somatic starch tested translocation