ELK4

Gene Name		ELK4, ETS-domain protein (SRF accessory protein 1)
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm
	Molecular Function	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Core Promoter Binding DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Cofactor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Cell Differentiation Histone H3 Deacetylation
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		10 interactors: BRCA1 FOS ID1 ID2 ID3 MAPK11 MAPK3 MAPK7 MAPK8 SRF
Entrez ID		2005
HPRD ID		02592
Ensembl ID		ENSG00000158711
Uniprot IDs		P28324 Q8IXL1
PDB IDs		1BC7 1BC8 1HBX 1K6O
Enriched GO Terms of Interacting Partners?		Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Cellular Response To Stress MAPK Cascade Regulation Of Innate Immune Response Cellular Response To Growth Factor Stimulus Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Signal Transduction By Phosphorylation Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Response To Growth Factor Negative Regulation Of Binding Regulation Of RNA Metabolic Process Cellular Response To Organic Substance Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Response To Stress Positive Regulation Of Gene Expression Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Immune System Process Response To Organic Substance Immune Response-regulating Signaling Pathway Negative Regulation Of Osteoblast Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Response To Abiotic Stimulus Regulation Of Binding Positive Regulation Of Immune Response Negative Regulation Of Ossification Regulation Of Immune System Process Immune System Process
Tagcloud ?		angiomatous cofactors ec elk1 ensured ensures exudative filopodia hallmarks hyaloid hypovascularization incomplete intraretinal macular mrtf neovascularization norrie pathologies plexi plexus protrusion reminiscent retinal srf telangiectasia tip vasculature vessels vitreoretinopathies