EDN2

Gene Name		endothelin 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space
	Molecular Function	Hormone Activity
	Biological Process	Prostaglandin Biosynthetic Process Temperature Homeostasis Positive Regulation Of Leukocyte Chemotaxis Hormonal Regulation Of The Force Of Heart Contraction Positive Regulation Of The Force Of Heart Contraction By Chemical Signal Regulation Of Systemic Arterial Blood Pressure By Endothelin Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Positive Regulation Of Cell Proliferation Positive Regulation Of Heart Rate Artery Smooth Muscle Contraction Vein Smooth Muscle Contraction Cytokine-mediated Signaling Pathway Regulation Of Vasoconstriction Calcium-mediated Signaling Neutrophil Chemotaxis Macrophage Activation Vasoconstriction Positive Regulation Of Smooth Muscle Contraction Inositol Phosphate-mediated Signaling Macrophage Chemotaxis Lung Alveolus Development Positive Regulation Of Prostaglandin-endoperoxide Synthase Activity Energy Homeostasis
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) G alpha (q) signalling events G alpha (q) signalling events Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: CMA1 KEL MME
Entrez ID		1907
HPRD ID		07173
Ensembl ID		ENSG00000127129
Uniprot IDs		P20800
PDB IDs
Enriched GO Terms of Interacting Partners?		Angiotensin Maturation Regulation Of Angiotensin Metabolic Process Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Blood Circulation Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Peptide Hormone Processing Regulation Of Systemic Arterial Blood Pressure Peptide Metabolic Process Interleukin-1 Beta Biosynthetic Process Regulation Of Blood Pressure Hormone Metabolic Process Proteolysis Protein Processing Cellular Amide Metabolic Process Cellular Response To UV-A Regulation Of Hormone Levels Creatinine Metabolic Process Cellular Magnesium Ion Homeostasis Response To UV-A Regulation Of Axon Diameter Cellular Response To UV-B Regulation Of Cell Projection Size Cellular Chemical Homeostasis Interleukin-1 Beta Production Negative Regulation Of Potassium Ion Transmembrane Transport Magnesium Ion Homeostasis Response To UV-B Replicative Senescence Organ Development Beta-amyloid Metabolic Process Cellular Homeostasis Negative Regulation Of Potassium Ion Transport Skeletal Muscle Fiber Development Cytokine Biosynthetic Process Myotube Cell Development Cytokine Metabolic Process Chemical Homeostasis Vasoconstriction Regulation Of Potassium Ion Transmembrane Transport System Development Negative Regulation Of Ion Transmembrane Transport Muscle Fiber Development Negative Regulation Of Transmembrane Transport Myotube Differentiation Cellular Response To UV Regulation Of Potassium Ion Transport Cellular Response To Glucose Stimulus Multicellular Organismal Development Anatomical Structure Development Cell Aging
Tagcloud ?		albino ameliorates bright damaging dawley functioning glial gs inos lif light lux macroglial maintaining muller neuroprotective nm photoreceptors preconditioning pretreatment proper qpcr ranging red retina retinal s100beta sprague vimentin