DMP1

Gene Name		dentin matrix acidic phosphoprotein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Nucleus Nucleoplasm Nucleolus Cytoplasm Intracellular Membrane-bounded Organelle
	Molecular Function	Integrin Binding Calcium Ion Binding Extracellular Matrix Binding
	Biological Process	Ossification Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Biomineral Tissue Development
Pathways		ECM proteoglycans
Drugs
Diseases
GWAS		Dental caries ( 23064961)
Protein-protein Interactions		2 interactors: CD44 CFH
Entrez ID		1758
HPRD ID		02989
Ensembl ID		ENSG00000152592
Uniprot IDs		Q13316
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Monocyte Aggregation Monocyte Aggregation Regulation Of Protein Processing Wound Healing Involved In Inflammatory Response Positive Regulation Of Heterotypic Cell-cell Adhesion Complement Activation, Alternative Pathway Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Hyaluronan Catabolic Process Innate Immune Response Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Branching Involved In Prostate Gland Morphogenesis Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Complement Activation Immune Response Defense Response Prostate Gland Epithelium Morphogenesis Hyaluronan Metabolic Process Prostate Gland Morphogenesis Regulation Of Signal Transduction By P53 Class Mediator Regulation Of Humoral Immune Response Glycosaminoglycan Catabolic Process Branching Involved In Ureteric Bud Morphogenesis Ureteric Bud Morphogenesis Prostate Gland Development Regulation Of Acute Inflammatory Response Positive Regulation Of Peptidyl-serine Phosphorylation Nephron Morphogenesis Renal Tubule Morphogenesis Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Extracellular Matrix Disassembly Renal Tubule Development Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Immune System Process Kidney Morphogenesis Regulation Of Protein Metabolic Process Regulation Of Peptidyl-serine Phosphorylation Ureteric Bud Development Mesonephric Tubule Development Mesonephric Epithelium Development Interferon-gamma-mediated Signaling Pathway Mesonephros Development Regulation Of Response To DNA Damage Stimulus Positive Regulation Of ERK1 And ERK2 Cascade Complement Activation Nephron Development
Tagcloud ?		7q21 adenosquamous alternatively deleted deposits diminishing dmp1alpha dmp1beta dmp1gamma haplo hemizygously hyperplasia indeed insufficient keratinized locus mmtv multifocal publicly seq spliced splicing surrounding transdifferentiation tumour tumourigenic tumours undefined upregulating