COL9A1

Gene Name		collagen, type IX, alpha 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Proteinaceous Extracellular Matrix Collagen Type IX Trimer Endoplasmic Reticulum Lumen
	Molecular Function	Extracellular Matrix Structural Constituent Conferring Tensile Strength Metal Ion Binding
	Biological Process	Tissue Homeostasis Growth Plate Cartilage Development Axon Guidance Organ Morphogenesis Extracellular Matrix Disassembly Extracellular Matrix Organization Collagen Catabolic Process
Pathways		Signaling by PDGF NCAM1 interactions Collagen formation Axon guidance Collagen degradation Degradation of the extracellular matrix ECM proteoglycans Integrin cell surface interactions Collagen biosynthesis and modifying enzymes NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: COL2A1 COMP MAG
Entrez ID		1297
HPRD ID		00367
Ensembl ID		ENSG00000112280
Uniprot IDs		B3KWS8 P20849
PDB IDs		2UUR
Enriched GO Terms of Interacting Partners?		Cartilage Development Involved In Endochondral Bone Morphogenesis Endochondral Bone Morphogenesis Bone Morphogenesis Cartilage Development Limb Development Bone Development Connective Tissue Development Skeletal System Morphogenesis Extracellular Matrix Organization Extracellular Structure Organization Limb Bud Formation Skeletal System Development Cellular Response To Growth Factor Stimulus Response To Growth Factor Otic Vesicle Development Organ Development Growth Plate Cartilage Development Embryonic Skeletal Joint Morphogenesis Embryonic Skeletal Joint Development Notochord Development Cartilage Condensation Cellular Response To BMP Stimulus Endochondral Bone Growth Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Substantia Nigra Development Central Nervous System Development Negative Regulation Of Cell Death Organ Morphogenesis Endochondral Ossification System Development Neural Nucleus Development Cell Adhesion Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Collagen Fibril Organization Negative Regulation Of Axonogenesis Collagen Catabolic Process Locomotion Multicellular Organismal Development Anatomical Structure Development Collagen Metabolic Process Multicellular Organismal Macromolecule Metabolic Process Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Chondrocyte Differentiation Midbrain Development Regulation Of Apoptotic Process Multicellular Organismal Metabolic Process Movement Of Cell Or Subcellular Component Extracellular Matrix Disassembly Regulation Of Cell Death
Tagcloud ?		ablation aggrecan betaig cartilage chondrocyte collagen comp compensatory disturbed endochondral epiphycan epiphyseal fibronectin hypocellular interactome ix knock matn3 matrilin null oligomeric osteoarthritis proteomic tgfbeta thrombospondin underpinning xii