TTC8

Gene Name		tetratricopeptide repeat domain 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Cytosol Cilium Photoreceptor Connecting Cilium BBSome Ciliary Basal Body Ciliary Membrane
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding
	Biological Process	Organelle Organization Axon Guidance Sensory Perception Of Smell Protein Transport Olfactory Bulb Development Regulation Of Protein Localization Nonmotile Primary Cilium Assembly Multicellular Organism Growth Cilium Assembly Fat Cell Differentiation Establishment Of Anatomical Structure Orientation Sensory Processing Camera-type Eye Photoreceptor Cell Differentiation Renal Tubule Development
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-protein Interactions		1 interactors: PCM1
Entrez ID		123016
HPRD ID		10484
Ensembl ID		ENSG00000165533
Uniprot IDs		B3KSL8 Q86U25 Q8TAM2
PDB IDs
Enriched GO Terms of Interacting Partners?		Intraciliary Transport Involved In Cilium Morphogenesis Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Protein Localization To Centrosome Interkinetic Nuclear Migration Protein Localization To Cytoskeleton Neuronal Stem Cell Maintenance Intraciliary Transport Cytoplasmic Microtubule Organization Nucleus Localization Cell Proliferation In Forebrain Microtubule Anchoring Centrosome Organization Neural Precursor Cell Proliferation Microtubule Organizing Center Organization G2/M Transition Of Mitotic Cell Cycle Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Maintenance Of Protein Location In Cell Maintenance Of Protein Location Stem Cell Maintenance Maintenance Of Location In Cell Positive Regulation Of Intracellular Protein Transport Cilium Assembly Cilium Organization Cilium Morphogenesis Positive Regulation Of Intracellular Transport Stem Cell Development Mitotic Cell Cycle Phase Transition Regulation Of Intracellular Protein Transport Cell Cycle Phase Transition
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