CLIC2

Gene Name		chloride intracellular channel 2
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Gene Ontology Annotations	Cellular Component	Intracellular Nucleus Cytoplasm Chloride Channel Complex
	Molecular Function	Glutathione Transferase Activity Glutathione Peroxidase Activity Voltage-gated Ion Channel Activity Chloride Channel Activity Protein Binding
	Biological Process	Transport Signal Transduction Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Binding Oxidation-reduction Process Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Chloride Transmembrane Transport
Pathways		Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS
Protein-protein Interactions		3 interactors: NEDD4 NEDD4L TRAPPC2
Entrez ID		1193
HPRD ID		02139
Ensembl ID		ENSG00000155962
Uniprot IDs		O15247
PDB IDs		2PER 2R4V 2R5G
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Sodium Ion Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Potassium Ion Transmembrane Transport Protein Monoubiquitination Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Potassium Ion Transport Regulation Of Sodium Ion Transport Negative Regulation Of Ion Transport Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Protein Polyubiquitination Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Caveolin-mediated Endocytosis Positive Regulation Of Protein Catabolic Process Regulation Of Membrane Potential Response To Metal Ion Regulation Of Caveolin-mediated Endocytosis Progesterone Receptor Signaling Pathway Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Negative Regulation Of Sodium Ion Transmembrane Transport Negative Regulation Of Transport Regulation Of Ion Transmembrane Transport Negative Regulation Of Protein Localization To Cell Surface Glucocorticoid Receptor Signaling Pathway Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Tight Junction Assembly Response To Inorganic Substance Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Targeting To Lysosome Negative Regulation Of Potassium Ion Transmembrane Transport Cellular Sodium Ion Homeostasis Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Protein Localization To Lysosome Protein Modification By Small Protein Conjugation Protein Catabolic Process Regulation Of Ion Transport Ventricular Cardiac Muscle Cell Action Potential Regulation Of Protein Localization To Cell Surface
Tagcloud ?		303c amplifying atrial cardiomegaly channel channelopathy channels chf comprised congestive disability exome fibrillation h101q id intellectual leaky neurotransmitter overly ryanodine ryr ryr2 ryrs seizures suffer transferase trigger utilizing vital