ADCYAP1R1

Gene Name		adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
Image
Gene Ontology Annotations	Cellular Component	Endosome Rough Endoplasmic Reticulum Plasma Membrane Integral Component Of Plasma Membrane Caveola Tight Junction Cell Surface Neuron Projection Receptor Complex
	Molecular Function	Receptor Activity Vasoactive Intestinal Polypeptide Receptor Activity Protein Binding Adenylate Cyclase Binding ADP-ribosylation Factor Binding Neuropeptide Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway G-protein Coupled Receptor Signaling Pathway Activation Of Adenylate Cyclase Activity Activation Of Phospholipase C Activity Spermatogenesis Positive Regulation Of Calcium Ion Transport Into Cytosol CAMP-mediated Signaling Cell Differentiation Response To Estradiol Multicellular Organismal Response To Stress Response To Drug Response To Ethanol Development Of Primary Female Sexual Characteristics Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of Cell Death Positive Regulation Of Inositol Phosphate Biosynthetic Process
Pathways		Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Signalling by NGF G alpha (s) signalling events Activation of TRKA receptors Glucagon-type ligand receptors NGF signalling via TRKA from the plasma membrane GPCR ligand binding Metabolic disorders of biological oxidation enzymes GPCR downstream signaling NGF-independant TRKA activation Class B/2 (Secretin family receptors)
Drugs
Diseases
GWAS		Major depressive disorder ( 21621269)
Protein-protein Interactions		2 interactors: ADCYAP1 CALM1
Entrez ID		117
HPRD ID		00045
Ensembl ID		ENSG00000078549
Uniprot IDs		P41586
PDB IDs		2JOD 3N94
Enriched GO Terms of Interacting Partners?		Activation Of Adenylate Cyclase Activity Positive Regulation Of Adenylate Cyclase Activity Positive Regulation Of Lyase Activity Regulation Of Adenylate Cyclase Activity Positive Regulation Of CAMP Biosynthetic Process Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Negative Regulation Of Ion Transport Regulation Of CAMP Metabolic Process Second-messenger-mediated Signaling Response To Glucocorticoid Response To Corticosteroid Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Somatostatin Secretion Negative Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Negative Regulation Of Transport Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Positive Regulation Of Protein Kinase Activity Response To Steroid Hormone Positive Regulation Of Kinase Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Transferase Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Growth Hormone Secretion Cellular Response To Growth Factor Stimulus Synaptic Transmission Response To Growth Factor Regulation Of Ion Transport Secretion Regulation Of Oligodendrocyte Progenitor Proliferation Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Growth Hormone Secretion Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Protein Phosphorylation Negative Regulation Of Glial Cell Proliferation Detection Of Calcium Ion Negative Regulation Of Inflammatory Response To Antigenic Stimulus Positive Regulation Of Transport Regulation Of Protein Kinase Activity Regulation Of Cell Communication By Electrical Coupling Brain Development Positive Regulation Of Phosphoprotein Phosphatase Activity
Tagcloud ?