CHRM5

Gene Name		cholinergic receptor, muscarinic 5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Junction Postsynaptic Membrane
	Molecular Function	Phosphatidylinositol Phospholipase C Activity G-protein Coupled Acetylcholine Receptor Activity
	Biological Process	Gastric Acid Secretion Adenylate Cyclase-inhibiting G-protein Coupled Acetylcholine Receptor Signaling Pathway G-protein Coupled Acetylcholine Receptor Signaling Pathway Metabolic Process Cell Proliferation Dopamine Transport Transmission Of Nerve Impulse Regulation Of Phosphatidylinositol Dephosphorylation
Pathways		G alpha (q) signalling events G alpha (q) signalling events Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Gastrin-CREB signalling pathway via PKC and MAPK Class A/1 (Rhodopsin-like receptors) Muscarinic acetylcholine receptors Amine ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs		Ziprasidone Amitriptyline Olanzapine Metixene Clozapine Trihexyphenidyl Promazine Imipramine Darifenacin Nortriptyline Atropine Nicardipine Paroxetine Homatropine Methylbromide Scopolamine Benzquinamide Propiomazine Cryptenamine Brompheniramine Maprotiline Tolterodine Promethazine Doxepin Desipramine Quetiapine Aripiprazole Chlorprothixene Methotrimeprazine Solifenacin Fesoterodine Aclidinium
Diseases
GWAS
Protein-protein Interactions		1 interactors: GPRASP1
Entrez ID		1133
HPRD ID		00331
Ensembl ID		ENSG00000184984
Uniprot IDs		P08912 Q8IVW0
PDB IDs
Enriched GO Terms of Interacting Partners?		G-protein Coupled Receptor Catabolic Process Receptor Catabolic Process Endosome To Lysosome Transport Lysosomal Transport Vacuolar Transport Receptor Metabolic Process Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Endosomal Transport
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