SP140

Gene Name		SP140 nuclear body protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm PML Body
	Molecular Function	DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Zinc Ion Binding
	Biological Process	Chromatin Remodeling Regulation Of Transcription, DNA-templated Defense Response
Pathways
Drugs
Diseases
GWAS		Chronic lymphocytic leukemia ( 18758461) Crohn's disease ( 21102463 23128233) Multiple sclerosis ( 21833088)
Protein-protein Interactions		1 interactors: SIRT2
Entrez ID		11262
HPRD ID		09780
Ensembl ID		ENSG00000079263
Uniprot IDs		B4DVW8 E7ESH9 E7EUR5 E9PFJ6 Q0VGE4 Q13342 Q3KR17 Q8IWJ1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Oligodendrocyte Progenitor Proliferation Negative Regulation Of Defense Response To Bacterium Cellular Response To Caloric Restriction Negative Regulation Of NLRP3 Inflammasome Complex Assembly Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Involved In Cellular Response To Hypoxia Chromatin Silencing At Telomere Positive Regulation Of Attachment Of Spindle Microtubules To Kinetochore Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Regulation Of Oligodendrocyte Progenitor Proliferation Regulation Of NLRP3 Inflammasome Complex Assembly Regulation Of Defense Response To Bacterium Ripoptosome Assembly Ripoptosome Assembly Involved In Necroptotic Process Positive Regulation Of Oocyte Maturation Tubulin Deacetylation Peptidyl-lysine Deacetylation Hepatocyte Growth Factor Receptor Signaling Pathway Positive Regulation Of Execution Phase Of Apoptosis Cellular Response To Hepatocyte Growth Factor Stimulus Positive Regulation Of Oocyte Development Positive Regulation Of Chromosome Segregation Regulation Of Exit From Mitosis Cellular Response To Epinephrine Stimulus Negative Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Meiotic Nuclear Division Response To Epinephrine Response To Redox State Chromatin Silencing At RDNA Regulation Of Attachment Of Spindle Microtubules To Kinetochore Regulation Of Execution Phase Of Apoptosis Cellular Response To Catecholamine Stimulus Phosphatidylinositol 3-kinase Signaling Histone H4 Deacetylation Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Necroptotic Process Protein ADP-ribosylation Histone H3 Deacetylation Positive Regulation Of DNA Binding Negative Regulation Of Autophagy Chromatin Silencing Regulation Of Meiosis Substantia Nigra Development Negative Regulation Of Reactive Oxygen Species Metabolic Process Protein Kinase B Signaling Programmed Necrotic Cell Death Myelination In Peripheral Nervous System Necrotic Cell Death Schwann Cell Development Regulation Of Myelination Negative Regulation Of Neural Precursor Cell Proliferation
Tagcloud ?		biliary binders bromodomain catalyzes cirrhosis diversified elusive expand finger fingers flag homeodomain isomerase isomerization l3 leukocyte list lymphocytic modules peptidylprolyl phd phosphopeptide pin1 platforms pthr reader sand tails versatile