CFHR3

Gene Name		complement factor H-related 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function
	Biological Process
Pathways		Regulation of Complement cascade Complement cascade Innate Immune System
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23536807) Complement C3 and C4 levels ( 23028341) Meningococcal disease ( 20694013) Nephropathy ( 21399633)
Protein-protein Interactions		2 interactors: C3 PRDX4
Entrez ID		10878
HPRD ID		05626
Ensembl ID		ENSG00000116785
Uniprot IDs		Q02985 Q6NSD3
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Male Germ Cell Proliferation Positive Regulation Of Type IIa Hypersensitivity Regulation Of Male Germ Cell Proliferation Positive Regulation Of Activation Of Membrane Attack Complex Positive Regulation Of Hypersensitivity Monocarboxylic Acid Metabolic Process Positive Regulation Of Apoptotic Cell Clearance Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Protein Maturation By Protein Folding Regulation Of Apoptotic Cell Clearance Complement Activation, Alternative Pathway Positive Regulation Of Inflammatory Response To Antigenic Stimulus I-kappaB Phosphorylation Positive Regulation Of Humoral Immune Response Positive Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Positive Regulation Of Protein Processing Regulation Of Triglyceride Biosynthetic Process 4-hydroxyproline Metabolic Process Carboxylic Acid Metabolic Process Positive Regulation Of Acute Inflammatory Response Organic Acid Metabolic Process Regulation Of Complement Activation Positive Regulation Vascular Endothelial Growth Factor Production Positive Regulation Of Lipid Storage Regulation Of Triglyceride Metabolic Process Positive Regulation Of Immunoglobulin Mediated Immune Response Protein Maturation Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Phagocytosis Positive Regulation Of Glucose Transport Regulation Of Humoral Immune Response I-kappaB Kinase/NF-kappaB Signaling Regulation Of Lipid Storage Regulation Of Phagocytosis Regulation Of Acute Inflammatory Response Positive Regulation Of Inflammatory Response Regulation Of Glucose Transport Positive Regulation Of Endocytosis Reactive Oxygen Species Metabolic Process Small Molecule Metabolic Process Cell Redox Homeostasis Positive Regulation Of Angiogenesis Complement Activation, Classical Pathway Regulation Of Lipid Biosynthetic Process Humoral Immune Response Mediated By Circulating Immunoglobulin Complement Activation Positive Regulation Of Adaptive Immune Response Male Gonad Development Protein Activation Cascade Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Tagcloud ?		acquiring arguing attachment c3 c5 cfhr1 cfhr2 cfhr4a complement convertase evade expense fba fhl hemolytic heparin m28 m55 m6 scl1 scl2 scr18 scr3 scr7 serotypes streptococcal streptococci uremic utilize