CDKN1C

Gene Name		cyclin-dependent kinase inhibitor 1C (p57, Kip2)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm
	Molecular Function	Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Development Kidney Development Cell Cycle Arrest Regulation Of Mitotic Cell Cycle Aging Myeloid Cell Differentiation Adrenal Gland Development Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Kinase Activity Multicellular Organism Growth Negative Regulation Of Phosphorylation Neuron Maturation Camera-type Eye Development Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Epithelial Cell Proliferation Digestive System Development Uterus Development Embryonic Placenta Morphogenesis Genetic Imprinting Negative Regulation Of Protein Serine/threonine Kinase Activity
Pathways
Drugs
Diseases
GWAS		Calcium levels ( 20705733)
Protein-protein Interactions		11 interactors: AKT1 CCND1 CCNE2 CDK4 FBXL12 LIMK1 MYOD1 NR4A2 PCNA RB1 SKP2
Entrez ID		1028
HPRD ID		02913
Ensembl ID		ENSG00000129757
Uniprot IDs		P49918
PDB IDs
Enriched GO Terms of Interacting Partners?		G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Mitotic Cell Cycle Process Mitotic Cell Cycle Cell Cycle Process Cell Cycle Response To Extracellular Stimulus Regulation Of Catalytic Activity Regulation Of Cell Cycle Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Response To UV-A Positive Regulation Of Cell Cycle Regulation Of Protein Kinase Activity Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Mitotic Cell Cycle Response To Lipid Regulation Of Cell Size Response To Organic Cyclic Compound Cell Division Response To Hormone Positive Regulation Of Cellular Metabolic Process Response To Inorganic Substance Positive Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Response To Steroid Hormone Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle Arrest Regulation Of Cell Cycle Process Chromosome Organization Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Phosphorylation Response To External Stimulus Regulation Of Transcription From RNA Polymerase II Promoter Response To Abiotic Stimulus Neuron Maturation System Development Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Organ Development Cellular Response To Extracellular Stimulus Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Growth Positive Regulation Of Cell Cycle Process Striated Muscle Cell Differentiation Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Organelle Organization Cellular Protein Modification Process
Tagcloud ?		2xglucocorticoid 2xgre agonism agonists beas bronchial budesonide ciclesonide combat dexamethasone dusp1 fluticasone formoterol furoate glucocorticoid glucocorticoids gre gsk9027 gw870086x ikk2 nr3c1 phosphoinositide propionate reporter rgs2 ru24858 suboptimal tsc22d3 viii