ATP6AP2

Gene Name		ATPase, H+ transporting, lysosomal accessory protein 2
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Gene Ontology Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane Neuron Projection Cell Body Extracellular Vesicular Exosome
	Molecular Function	Aspartic-type Endopeptidase Activity Receptor Activity Protein Binding Enzyme Binding
	Biological Process	Angiotensin Maturation Proteolysis Rostrocaudal Neural Tube Patterning Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Transforming Growth Factor Beta1 Production Regulation Of MAPK Cascade Cellular Protein Metabolic Process Eye Pigmentation Head Morphogenesis
Pathways		Peptide hormone metabolism Metabolism of Angiotensinogen to Angiotensins
Drugs
Diseases
GWAS
Protein-protein Interactions		4 interactors: AGT REN VKORC1 ZBTB16
Entrez ID		10159
HPRD ID		06454
Ensembl ID		ENSG00000182220
Uniprot IDs		B7Z1I9 B7Z413 B7Z9I3 O75787
PDB IDs		3LBS 3LC8
Enriched GO Terms of Interacting Partners?		Renin-angiotensin Regulation Of Aldosterone Production Drinking Behavior Mesonephros Development Angiotensin Maturation Regulation Of Angiotensin Metabolic Process Regulation Of Blood Volume By Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Kidney Development Renal System Development Peptide Hormone Processing Urogenital System Development Negative Regulation Of Cell Proliferation Regulation Of Systemic Arterial Blood Pressure Renal System Process Feeding Behavior Developmental Process Involved In Reproduction Uterine Smooth Muscle Contraction Angiotensin Mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Positive Regulation Of Cell Differentiation Peptide Metabolic Process Organ Development Protein Localization To Nucleus Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Positive Regulation Of Protein Kinase C Activity Catenin Import Into Nucleus Renal Response To Blood Flow Involved In Circulatory Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure Regulation Of Blood Pressure Hormone Metabolic Process Angiotensin-mediated Drinking Behavior Smooth Muscle Cell Proliferation Positive Regulation Of NAD(P)H Oxidase Activity Positive Regulation Of Extracellular Matrix Constituent Secretion G-protein Coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Ovarian Follicle Rupture Regulation Of Renal Output By Angiotensin Single Organism Reproductive Process Gonad Development Development Of Primary Sexual Characteristics Protein Processing Fibroblast Proliferation Astrocyte Activation Reproductive Process Cellular Amide Metabolic Process Regulation Of Hormone Levels Positive Regulation Of NK T Cell Differentiation Regulation Of Blood Vessel Size By Renin-angiotensin Sex Differentiation Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Positive Regulation Of Activation Of JAK2 Kinase Activity
Tagcloud ?		amnion beta1 born endoperoxide fetal finger glucocorticoids integrity intrauterine labor maintaining membranes namely postulated preterm profibrotic promyelocytic prorenin prostaglandin ptgs2 regulate regulators renin sex stimulate synthase tgfb1 transforming zinc